Advancement: Bioelectronic device for ion fluxes control

Speaker Name: 
Manping Jia
Speaker Title: 
PhD Student (Advisor: Marco Rolandi)
Speaker Organization: 
Electrical Engineering
Start Time: 
Tuesday, June 4, 2019 - 10:00am
End Time: 
Tuesday, June 4, 2019 - 11:30am
Baskin Engineering, Room 330
Marco Rolandi

Abstract:  Bioelectronic is a growing interdisciplinary field which has great significance in a broad variety of meaningful applications, from biosensors, drug delivery to health monitoring systems, and brain-machine interface. Electrical devices are composed of hard materials, like metals, and use electrons to transfer signals. However, the biological system is made of fragile soft tissue, and use ions and biomolecules as the “language” to communicate. The integration of electronic devices and biological systems is always limited by their interface. Thus, materials with low Young’s moduli, like polymers, hydrogels, provide an excellent solution for the interface, because they share similarities in chemical “nature” with biological systems and could be engineered on different forms on electrical devices.
Here I propose to build ion pumps that could deliver and remove ions (H+, K+, Na+, Cl-) with high spatiotemporal resolution. In the device exploration, I mainly focus on the materials, including metal nanoparticles, ionic conductive polymers. Also, considering the critical function of ionic conductive polymers in bioelectronic devices, I discussed the proton conductivity measurement of biomaterials, including keratan sulfate and other glycosaminoglycans (GAG), using Pd/PdHx electrodes.