Humans of BSOE
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Scientific Principles of Life with Professor David Haussler
Dr. David Haussler
Distinguished Professor, Biomolecular Engineering
Learn basic principles of life as it exists on this planet and how they generalize -- Darwinian evolution, genomes -- scientific theories of life including mechanistic, thermodynamic, and information theoretic models. Explore the future of life from the Internet to machine learning and adaptation,... Read More
Defense: Comparative genomics and regulation of tRNAs and tRNA fragments
Andrew Holmes
PhD Candidate
Abstract: I report on two different forms of whole-genome analysis of tRNA gene regulation. The first is analysis of tRNA fragments using RNA-sequencing. I develop a computational method to analyze changes in RNA sequencing data from tRNAs and tRNA fragments and use this method to analyze... Read More
Advancement: Investigating RNA modifications in cancer through site-directed A-to-I editing for inosine identification in nvRNA sequencing
Alison Tang
PhD Student
Abstract: There are upwards of 100 distinct mRNA modifications that can alter mRNA stability, activity, and localization. One such RNA modification is the deamination of an adenosine to form an inosine, a modification that has been implicated in several cancers. To systematically study A-to-I... Read More
