# file generated by correlated-columns # ReadA2M T0280.t04-thin40.a2m.gz # SetMinSep 7 # SetMinPairs 0.7 requires 33 occupied positions in both columns # resulting in 10879 column pairs to test # reporting E-value <= 20 # MutualInfoSignif T0280.t04-thin40.mi.constraints # # There are 208 columns and 47 sequences # mean and standard deviation of log(E_value) for pairs not reported: 7.88971 1.26586 # mean and standard deviation of log(E_value) for all pairs: 7.76547 1.57624 # found 198 significant column pairs col1 col2 occupation info1 info2 mut_info mean_rand corr_mut_info e_value log_e_value Z_score 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 31 175 35 3.290297 3.347439 2.377206 1.792022 0.585184 1.500581e-04 -8.804488 -13.188052 96 156 44 2.996300 2.699388 1.734621 1.070279 0.664341 4.017466e-04 -7.819689 -12.410082 156 188 33 2.716860 3.032163 1.981567 1.279340 0.702227 4.209274e-04 -7.773050 -12.373239 129 156 45 2.337541 2.793143 1.288583 0.702282 0.586301 1.168783e-03 -6.751792 -11.566467 31 69 37 3.341361 2.948677 2.029758 1.475991 0.553767 6.963981e-03 -4.967004 -10.156523 77 156 41 3.465264 2.571096 1.770391 1.234539 0.535852 1.291405e-02 -4.349440 -9.668661 84 180 34 3.660130 3.533671 2.657952 2.258288 0.399664 1.593634e-02 -4.139153 -9.502539 129 188 34 2.165161 3.075591 1.462976 0.852350 0.610626 2.969910e-02 -3.516638 -9.010766 27 129 35 3.146881 2.227627 1.474354 0.879650 0.594704 4.364243e-02 -3.131725 -8.706693 49 96 42 3.769961 2.925105 2.120952 1.688103 0.432849 5.678544e-02 -2.868475 -8.498731 57 170 34 2.910602 3.064110 1.861350 1.349368 0.511982 7.216501e-02 -2.628800 -8.309393 121 146 45 1.873547 3.638874 1.279924 0.787508 0.492417 7.252848e-02 -2.623776 -8.305424 117 143 43 2.931511 2.395189 1.408821 0.904633 0.504188 7.383555e-02 -2.605915 -8.291314 164 185 34 3.075591 2.744422 1.835779 1.282759 0.553020 9.724449e-02 -2.330527 -8.073764 175 188 34 3.087073 3.075591 1.987541 1.483741 0.503800 9.829149e-02 -2.319818 -8.065304 96 129 46 3.050205 2.304306 1.274914 0.809629 0.465285 9.856288e-02 -2.317061 -8.063126 58 71 40 2.545049 2.580710 1.340929 0.853290 0.487640 1.170679e-01 -2.145001 -7.927202 131 185 33 2.175214 2.762125 1.409850 0.838548 0.571302 1.190839e-01 -2.127927 -7.913714 27 73 33 3.085934 2.790438 1.836865 1.311959 0.524906 1.519648e-01 -1.884107 -7.721101 42 60 34 3.241260 2.695551 1.839098 1.354375 0.484722 1.748353e-01 -1.743911 -7.610350 86 103 43 3.090860 3.298731 1.824247 1.416887 0.407360 1.804033e-01 -1.712560 -7.585583 156 184 34 2.765825 2.664805 1.625803 1.085953 0.539850 1.929634e-01 -1.645255 -7.532413 79 117 42 3.423193 2.903758 1.886399 1.459895 0.426504 2.695756e-01 -1.310906 -7.268286 41 56 39 2.872837 3.328415 1.835703 1.399158 0.436545 3.071725e-01 -1.180346 -7.165146 156 178 36 2.766333 1.626901 1.168839 0.649716 0.519123 3.349465e-01 -1.093784 -7.096764 96 186 34 2.881765 3.398465 2.064870 1.605010 0.459860 3.480534e-01 -1.055399 -7.066441 164 186 35 3.117751 3.431400 2.148718 1.731375 0.417343 3.754481e-01 -0.979635 -7.006589 34 129 41 2.958274 2.310366 1.249963 0.796239 0.453723 4.620289e-01 -0.772128 -6.842662 102 134 44 3.396519 2.692848 1.670263 1.259510 0.410753 4.908977e-01 -0.711519 -6.794783 134 147 47 2.709266 1.948815 1.202817 0.716727 0.486090 4.923959e-01 -0.708472 -6.792376 134 168 42 2.764591 3.494476 1.825432 1.410846 0.414586 4.925573e-01 -0.708144 -6.792117 77 129 43 3.491533 2.297027 1.414880 0.969768 0.445111 4.944307e-01 -0.704348 -6.789118 42 52 41 3.349291 2.713061 1.738081 1.291274 0.446807 5.652195e-01 -0.570541 -6.683413 29 117 39 3.110302 2.914525 1.794841 1.347322 0.447519 6.623047e-01 -0.412029 -6.558193 168 185 33 3.460616 2.776851 1.969123 1.547166 0.421957 7.340826e-01 -0.309134 -6.476907 29 96 42 3.105455 3.127430 1.831274 1.405751 0.425523 7.524159e-01 -0.284466 -6.457420 85 104 46 3.819135 3.158475 2.079155 1.743506 0.335649 7.549464e-01 -0.281109 -6.454768 95 186 33 3.240582 3.402551 2.253577 1.864364 0.389213 8.509464e-01 -0.161406 -6.360206 28 131 33 3.145272 2.300028 1.537565 1.066290 0.471275 9.573728e-01 -0.043562 -6.267111 28 156 34 3.185374 2.805586 1.830255 1.378105 0.452150 1.018736e+00 0.018562 -6.218034 34 156 39 2.885005 2.677978 1.560635 1.072502 0.488133 1.084042e+00 0.080696 -6.168950 96 174 39 2.792260 2.595666 1.435195 0.989632 0.445563 1.146762e+00 0.136942 -6.124517 96 178 36 2.901904 1.626901 1.147870 0.690767 0.457102 1.192442e+00 0.176003 -6.093660 113 156 41 3.298469 2.599566 1.574786 1.169593 0.405193 1.330748e+00 0.285741 -6.006969 57 113 37 3.164893 3.438486 2.049727 1.694507 0.355220 1.458244e+00 0.377233 -5.934692 156 191 33 2.802753 2.774883 1.609296 1.149813 0.459483 1.479013e+00 0.391375 -5.923521 22 129 33 3.518196 2.207336 1.560519 1.099663 0.460856 1.491952e+00 0.400085 -5.916639 181 188 33 2.546746 3.032163 1.671175 1.205892 0.465283 1.536200e+00 0.429312 -5.893551 82 137 46 3.476715 3.390106 2.077486 1.726861 0.350625 1.600472e+00 0.470298 -5.861173 128 190 33 1.174514 2.535485 0.828759 0.414693 0.414066 1.614959e+00 0.479310 -5.854054 138 175 40 3.219100 3.340469 2.044257 1.683763 0.360494 1.629823e+00 0.488472 -5.846816 134 158 38 2.600394 3.216339 1.693934 1.253253 0.440681 1.734871e+00 0.550933 -5.797473 94 174 37 3.049125 2.646001 1.512001 1.077205 0.434796 1.793612e+00 0.584232 -5.771168 35 77 38 3.469406 3.510664 2.300817 1.983491 0.317327 1.844583e+00 0.612253 -5.749031 92 134 44 3.268014 2.774025 1.564863 1.200491 0.364372 1.956056e+00 0.670930 -5.702678 83 148 45 3.392739 1.754028 1.154558 0.755274 0.399283 1.961270e+00 0.673592 -5.700575 31 152 42 3.327955 3.683402 2.190468 1.868333 0.322136 2.044734e+00 0.715268 -5.667652 158 175 34 3.118766 3.231009 2.012600 1.621815 0.390785 2.291459e+00 0.829189 -5.577657 89 186 33 2.714277 3.422401 1.914084 1.512927 0.401157 2.296276e+00 0.831289 -5.575998 134 185 34 3.021615 2.744422 1.708561 1.262271 0.446290 2.343538e+00 0.851662 -5.559904 127 139 46 0.495969 1.937247 0.282195 0.092512 0.189683 2.359610e+00 0.858496 -5.554505 122 149 45 3.425900 2.989200 1.729129 1.384967 0.344162 2.555134e+00 0.938105 -5.491616 69 152 40 2.916430 3.677567 1.972069 1.611346 0.360724 2.575612e+00 0.946087 -5.485310 175 184 35 3.222739 2.627351 1.678228 1.279626 0.398602 2.611125e+00 0.959781 -5.474492 80 112 35 3.106598 3.514159 2.108892 1.749941 0.358951 2.646496e+00 0.973236 -5.463863 55 128 41 3.096329 0.943558 0.711613 0.406889 0.304724 2.656261e+00 0.976920 -5.460953 74 114 41 3.230357 3.311447 1.973630 1.610129 0.363501 2.660101e+00 0.978364 -5.459812 49 129 42 3.769961 2.303680 1.535474 1.161294 0.374179 2.773406e+00 1.020076 -5.426860 76 102 37 3.254902 3.124088 1.967098 1.588501 0.378597 2.907506e+00 1.067296 -5.389558 98 114 44 3.143743 3.457228 1.812216 1.512959 0.299256 3.027308e+00 1.107674 -5.357660 96 188 33 2.797759 3.032163 1.763245 1.329157 0.434087 3.053644e+00 1.116336 -5.350817 92 129 44 3.268014 2.277473 1.202405 0.795109 0.407296 3.111126e+00 1.134985 -5.336085 87 95 43 3.204735 3.447344 1.912088 1.570510 0.341578 3.230282e+00 1.172569 -5.306394 84 129 45 3.752283 2.316553 1.454977 1.077772 0.377205 3.431445e+00 1.232981 -5.258670 72 79 43 3.204198 3.502934 1.987992 1.656089 0.331903 3.480675e+00 1.247226 -5.247417 129 157 46 2.327253 1.822022 0.626562 0.299300 0.327263 3.499781e+00 1.252700 -5.243092 71 92 44 2.733701 3.268014 1.485687 1.089441 0.396246 3.503594e+00 1.253789 -5.242232 96 113 43 2.873371 3.416442 1.739164 1.388592 0.350572 3.526798e+00 1.260391 -5.237017 158 168 35 3.034991 3.438961 2.040799 1.677634 0.363164 3.569026e+00 1.272293 -5.227615 29 60 33 2.967748 2.689383 1.678230 1.247402 0.430827 3.842868e+00 1.346219 -5.169214 95 129 45 3.469770 2.308491 1.308056 0.934157 0.373900 3.963396e+00 1.377101 -5.144818 124 187 34 1.654843 2.980826 1.022882 0.608072 0.414809 3.976152e+00 1.380315 -5.142280 28 46 33 3.202852 3.022302 1.930907 1.549425 0.381482 3.994990e+00 1.385041 -5.138546 31 93 41 3.291620 3.495003 2.051260 1.726120 0.325140 4.074514e+00 1.404751 -5.122975 128 186 34 1.151549 3.398465 1.011699 0.612856 0.398843 4.091243e+00 1.408849 -5.119738 58 109 39 2.582244 3.125432 1.569835 1.184499 0.385336 4.149987e+00 1.423105 -5.108476 79 152 45 3.474457 3.691419 2.196462 1.925608 0.270854 4.330988e+00 1.465796 -5.074751 75 134 40 3.020482 2.569973 1.568527 1.147039 0.421487 4.366631e+00 1.473992 -5.068277 75 100 37 3.116861 3.902304 2.350252 2.044368 0.305884 4.413418e+00 1.484649 -5.059857 95 167 40 3.401205 3.256844 1.973865 1.636980 0.336885 4.456253e+00 1.494308 -5.052227 41 156 40 2.878320 2.473624 1.319611 0.945222 0.374389 4.547292e+00 1.514532 -5.036251 28 105 33 3.145272 3.510176 2.217115 1.865113 0.352002 4.721843e+00 1.552199 -5.006494 28 129 34 3.185374 2.238403 1.329680 0.939582 0.390098 4.797827e+00 1.568163 -4.993883 72 110 36 3.124768 3.398413 2.030048 1.680867 0.349182 4.826591e+00 1.574140 -4.989162 33 128 41 2.816402 0.943558 0.677460 0.363428 0.314032 5.339645e+00 1.675159 -4.909359 134 150 47 2.709266 3.146071 1.410087 1.071288 0.338799 5.592647e+00 1.721453 -4.872788 55 170 36 3.152447 3.013657 1.805052 1.419168 0.385884 5.617490e+00 1.725885 -4.869287 156 174 39 2.830310 2.462403 1.290365 0.911394 0.378971 5.788053e+00 1.755796 -4.845658 27 74 34 3.127781 3.138502 1.892487 1.530082 0.362405 5.817875e+00 1.760935 -4.841598 55 74 37 3.148944 3.111463 1.848515 1.468651 0.379865 5.850900e+00 1.766595 -4.837126 179 186 34 3.231769 3.339642 2.094386 1.759319 0.335067 5.969776e+00 1.786709 -4.821237 93 152 44 3.507743 3.691831 2.229001 1.963838 0.265162 6.049120e+00 1.799913 -4.810806 31 72 40 3.294588 3.193943 1.894588 1.557000 0.337589 6.175134e+00 1.820531 -4.794519 37 156 37 2.587569 2.449132 1.158629 0.804430 0.354199 6.178081e+00 1.821008 -4.794142 39 151 40 3.343542 1.628390 0.991291 0.624606 0.366685 6.196248e+00 1.823944 -4.791822 55 129 41 3.096329 2.349939 1.207602 0.825595 0.382007 6.412899e+00 1.858311 -4.764673 69 129 40 2.916430 2.345462 1.153197 0.785808 0.367389 6.458958e+00 1.865468 -4.759019 36 79 40 3.406198 3.575071 2.197085 1.896578 0.300507 6.495703e+00 1.871141 -4.754537 39 81 40 3.343542 3.395462 2.026189 1.709002 0.317188 6.557184e+00 1.880561 -4.747096 108 146 41 3.515460 3.555740 2.250233 1.942152 0.308081 6.610076e+00 1.888595 -4.740749 117 146 43 2.931511 3.597679 1.870822 1.547028 0.323794 6.803274e+00 1.917404 -4.717991 51 121 40 3.055221 1.901519 1.022957 0.648353 0.374603 6.824390e+00 1.920503 -4.715543 34 174 34 2.841275 2.558937 1.460383 1.071237 0.389146 6.880733e+00 1.928725 -4.709047 104 191 33 3.243609 2.835489 1.830603 1.448872 0.381731 7.005661e+00 1.946719 -4.694833 54 96 42 3.358367 3.051305 1.815206 1.496747 0.318459 7.096288e+00 1.959572 -4.684679 118 129 43 2.118385 2.297027 0.743987 0.432608 0.311378 7.112943e+00 1.961916 -4.682827 29 154 42 3.105455 1.776345 1.066598 0.688026 0.378572 7.179573e+00 1.971240 -4.675462 61 134 34 3.623509 2.525127 1.811461 1.489009 0.322452 7.348148e+00 1.994448 -4.657127 37 79 38 2.567817 3.632557 1.709154 1.350048 0.359106 7.433168e+00 2.005952 -4.648040 71 143 46 2.733092 2.420809 1.065470 0.705917 0.359553 7.725229e+00 2.044491 -4.617594 55 71 41 3.096329 2.703292 1.405723 1.056561 0.349162 7.765698e+00 2.049716 -4.613467 89 159 33 2.971557 3.119370 1.827577 1.453380 0.374197 7.814660e+00 2.056001 -4.608502 85 111 37 3.843796 3.180841 2.268019 1.995622 0.272397 7.822542e+00 2.057010 -4.607705 72 129 44 3.193737 2.327560 1.193102 0.845488 0.347614 7.852699e+00 2.060857 -4.604666 136 189 35 2.335270 3.328724 1.480981 1.097006 0.383975 8.004092e+00 2.079953 -4.589581 49 156 40 3.765957 2.494993 1.729263 1.403329 0.325934 8.397252e+00 2.127905 -4.551700 126 190 33 1.593177 2.535485 0.863937 0.535737 0.328200 8.489180e+00 2.138792 -4.543099 120 173 37 2.023727 2.156067 0.932594 0.540873 0.391721 8.594923e+00 2.151172 -4.533319 68 92 38 2.659038 3.264136 1.557083 1.211316 0.345767 8.659347e+00 2.158639 -4.527420 42 129 44 3.415612 2.321839 1.295177 0.962616 0.332561 8.801737e+00 2.174949 -4.514536 100 107 38 3.935446 3.239440 2.367877 2.099012 0.268865 8.870386e+00 2.182718 -4.508398 27 156 35 3.146881 2.774475 1.656778 1.295449 0.361329 8.948070e+00 2.191438 -4.501510 29 156 40 3.010964 2.658828 1.458024 1.098150 0.359874 9.291691e+00 2.229121 -4.471741 126 173 37 1.486537 2.156067 0.784412 0.406885 0.377527 9.351054e+00 2.235489 -4.466710 105 152 45 3.508334 3.691419 2.196788 1.936801 0.259987 9.669730e+00 2.269000 -4.440237 111 155 36 3.161487 2.378879 1.402698 1.029828 0.372871 9.706145e+00 2.272759 -4.437268 109 156 43 3.354793 2.602034 1.533339 1.191178 0.342160 9.950064e+00 2.297579 -4.417661 35 46 39 3.355325 3.149499 1.956726 1.637971 0.318755 9.967848e+00 2.299365 -4.416250 172 185 33 2.621064 2.762125 1.460600 1.070270 0.390330 1.009028e+01 2.311572 -4.406606 87 170 38 3.198182 2.995722 1.714905 1.370550 0.344356 1.019776e+01 2.322168 -4.398236 102 159 33 3.111835 3.119370 1.861498 1.538570 0.322928 1.078133e+01 2.377816 -4.354275 94 126 43 3.154928 1.498789 0.879442 0.577494 0.301948 1.111776e+01 2.408544 -4.330001 74 87 39 3.225956 3.205007 1.850939 1.535376 0.315563 1.120860e+01 2.416682 -4.323572 72 178 34 2.976450 1.512413 0.993722 0.637931 0.355792 1.133549e+01 2.427939 -4.314679 132 185 34 1.273034 2.744422 0.849438 0.481199 0.368239 1.165078e+01 2.455374 -4.293006 51 176 35 3.071683 3.571302 2.128267 1.794724 0.333543 1.171871e+01 2.461187 -4.288414 57 129 39 3.153133 2.327016 1.246530 0.889483 0.357047 1.196854e+01 2.482281 -4.271750 84 109 45 3.752283 3.357651 2.174070 1.891438 0.282633 1.205657e+01 2.489610 -4.265960 42 102 42 3.443544 3.424956 2.047611 1.771805 0.275806 1.206116e+01 2.489990 -4.265660 62 129 33 3.366089 2.270186 1.471261 1.069197 0.402064 1.212795e+01 2.495513 -4.261297 55 156 39 3.100778 2.385982 1.310617 0.966278 0.344338 1.216790e+01 2.498801 -4.258700 138 167 42 3.195540 3.224869 1.814271 1.533854 0.280418 1.218818e+01 2.500466 -4.257384 73 102 40 2.817110 3.242965 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