# file generated by correlated-columns # ReadA2M T0248.t04-thin35.a2m.gz # SetMinSep 7 # SetMinPairs 0.7 requires 6 occupied positions in both columns # resulting in 20906 column pairs to test # reporting E-value <= 100 # MutualInfoSignif T0248.t04-thin35.mi.constraints # # There are 294 columns and 8 sequences # mean and standard deviation of log(E_value) for pairs not reported: 9.12042 1.04147 # mean and standard deviation of log(E_value) for all pairs: 9.06104 1.22106 # found 187 significant column pairs col1 col2 occupation info1 info2 mut_info mean_rand corr_mut_info e_value log_e_value Z_score 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 151 175 7 2.521641 2.521641 2.521641 2.248212 0.273429 5.708430e-02 -2.863226 -11.506446 242 262 7 2.521641 2.521641 2.521641 2.248498 0.273143 7.363963e-02 -2.608572 -11.261932 65 175 7 2.521641 2.521641 2.521641 2.248783 0.272857 9.394932e-02 -2.365000 -11.028059 66 146 7 2.521641 2.521641 2.521641 2.249069 0.272571 1.186245e-01 -2.131792 -10.804138 236 268 7 2.521641 2.521641 2.521641 2.249355 0.272286 1.483335e-01 -1.908292 -10.589538 79 119 7 2.235926 2.235926 2.235926 1.712641 0.523286 1.948174e-01 -1.635693 -10.327793 125 167 7 2.521641 2.521641 2.521641 2.250498 0.271143 3.328585e-01 -1.100038 -9.813469 242 268 7 2.521641 2.521641 2.521641 2.250498 0.271143 3.328585e-01 -1.100038 -9.813469 65 151 7 2.521641 2.521641 2.521641 2.250783 0.270857 3.997339e-01 -0.916956 -9.637677 236 262 7 2.521641 2.521641 2.521641 2.250926 0.270714 4.369367e-01 -0.827967 -9.552232 92 147 7 2.521641 2.521641 2.521641 2.251926 0.269714 7.800067e-01 -0.248453 -8.995794 124 270 6 2.251629 2.251629 2.251629 1.936629 0.315000 8.119358e-01 -0.208334 -8.957273 80 164 7 2.235926 2.235926 2.235926 1.720926 0.515000 8.296230e-01 -0.186784 -8.936581 86 121 7 2.235926 2.235926 2.235926 1.720355 0.515571 8.857153e-01 -0.121360 -8.873762 89 254 6 2.251629 2.251629 2.251629 1.936963 0.314667 9.473067e-01 -0.054132 -8.809212 79 277 6 2.251629 2.251629 2.251629 1.937296 0.314333 1.099442e+00 0.094803 -8.666207 254 283 6 2.251629 2.251629 2.251629 1.937629 0.314000 1.269652e+00 0.238743 -8.527999 127 212 6 2.251629 2.251629 2.251629 1.937796 0.313833 1.361951e+00 0.308918 -8.460618 135 212 6 2.251629 2.251629 2.251629 1.937963 0.313667 1.459272e+00 0.377937 -8.394347 217 268 6 2.251629 2.251629 2.251629 1.937963 0.313667 1.459272e+00 0.377937 -8.394347 242 283 6 2.251629 2.251629 2.251629 1.938296 0.313333 1.669664e+00 0.512623 -8.265026 236 284 6 2.251629 2.251629 2.251629 1.938463 0.313167 1.783082e+00 0.578343 -8.201922 82 125 6 2.251629 2.251629 2.251629 1.938629 0.313000 1.902212e+00 0.643018 -8.139823 161 266 6 2.251629 2.251629 2.251629 1.938629 0.313000 1.902212e+00 0.643018 -8.139823 234 284 6 2.251629 2.251629 2.251629 1.938629 0.313000 1.902212e+00 0.643018 -8.139823 153 264 6 2.251629 2.251629 2.251629 1.938796 0.312833 2.027232e+00 0.706671 -8.078704 217 236 6 2.251629 2.251629 2.251629 1.938796 0.312833 2.027232e+00 0.706671 -8.078704 69 246 6 2.251629 2.251629 2.251629 1.938963 0.312667 2.158316e+00 0.769328 -8.018542 217 242 6 2.251629 2.251629 2.251629 1.938963 0.312667 2.158316e+00 0.769328 -8.018542 66 135 6 2.251629 2.251629 2.251629 1.939129 0.312500 2.295641e+00 0.831012 -7.959315 119 277 6 2.251629 2.251629 2.251629 1.939129 0.312500 2.295641e+00 0.831012 -7.959315 217 284 6 2.251629 2.251629 2.251629 1.939296 0.312333 2.439386e+00 0.891746 -7.900999 262 284 6 2.251629 2.251629 2.251629 1.939296 0.312333 2.439386e+00 0.891746 -7.900999 82 107 6 2.251629 2.251629 2.251629 1.939463 0.312167 2.589728e+00 0.951553 -7.843574 124 187 6 2.251629 2.251629 2.251629 1.939463 0.312167 2.589728e+00 0.951553 -7.843574 156 264 6 2.251629 2.251629 2.251629 1.939463 0.312167 2.589728e+00 0.951553 -7.843574 107 254 6 2.251629 2.251629 2.251629 1.939629 0.312000 2.746845e+00 1.010453 -7.787019 135 146 6 2.251629 2.251629 2.251629 1.939629 0.312000 2.746845e+00 1.010453 -7.787019 176 212 6 2.251629 2.251629 2.251629 1.939629 0.312000 2.746845e+00 1.010453 -7.787019 217 254 6 2.251629 2.251629 2.251629 1.939629 0.312000 2.746845e+00 1.010453 -7.787019 217 262 6 2.251629 2.251629 2.251629 1.939629 0.312000 2.746845e+00 1.010453 -7.787019 69 213 6 2.251629 2.251629 2.251629 1.939796 0.311833 2.910916e+00 1.068468 -7.731314 73 264 6 2.251629 2.251629 2.251629 1.939796 0.311833 2.910916e+00 1.068468 -7.731314 217 234 6 2.251629 2.251629 2.251629 1.939796 0.311833 2.910916e+00 1.068468 -7.731314 236 283 6 2.251629 2.251629 2.251629 1.939796 0.311833 2.910916e+00 1.068468 -7.731314 73 101 6 2.251629 2.251629 2.251629 1.939963 0.311667 3.082120e+00 1.125618 -7.676441 92 270 6 2.251629 2.251629 2.251629 1.939963 0.311667 3.082120e+00 1.125618 -7.676441 153 266 6 2.251629 2.251629 2.251629 1.939963 0.311667 3.082120e+00 1.125618 -7.676441 268 283 6 2.251629 2.251629 2.251629 1.939963 0.311667 3.082120e+00 1.125618 -7.676441 101 161 6 2.251629 2.251629 2.251629 1.940129 0.311500 3.260634e+00 1.181922 -7.622378 264 274 6 2.251629 2.251629 2.251629 1.940129 0.311500 3.260634e+00 1.181922 -7.622378 73 266 6 2.251629 2.251629 2.251629 1.940463 0.311167 3.640310e+00 1.292069 -7.516617 146 212 6 2.251629 2.251629 2.251629 1.940629 0.311000 3.841827e+00 1.345948 -7.464884 135 148 6 2.251629 2.251629 2.251629 1.940796 0.310833 4.051368e+00 1.399055 -7.413892 139 211 6 2.251629 2.251629 2.251629 1.940796 0.310833 4.051368e+00 1.399055 -7.413892 85 211 6 2.251629 2.251629 2.251629 1.940963 0.310667 4.269109e+00 1.451405 -7.363626 148 212 6 2.251629 2.251629 2.251629 1.940963 0.310667 4.269109e+00 1.451405 -7.363626 57 187 6 2.251629 2.251629 2.251629 1.941129 0.310500 4.495226e+00 1.503016 -7.314071 135 176 6 2.251629 2.251629 2.251629 1.941463 0.310167 4.973290e+00 1.604082 -7.217029 147 270 6 2.251629 2.251629 2.251629 1.941629 0.310000 5.225587e+00 1.653567 -7.169514 161 264 6 2.251629 2.251629 2.251629 1.941629 0.310000 5.225587e+00 1.653567 -7.169514 163 187 6 2.251629 2.251629 2.251629 1.941796 0.309833 5.486957e+00 1.702374 -7.122651 254 284 6 2.251629 2.251629 2.251629 1.941796 0.309833 5.486957e+00 1.702374 -7.122651 262 283 6 2.251629 2.251629 2.251629 1.941796 0.309833 5.486957e+00 1.702374 -7.122651 82 167 6 2.251629 2.251629 2.251629 1.941963 0.309667 5.757574e+00 1.750516 -7.076426 127 187 6 2.251629 2.251629 2.251629 1.941963 0.309667 5.757574e+00 1.750516 -7.076426 242 284 6 2.251629 2.251629 2.251629 1.941963 0.309667 5.757574e+00 1.750516 -7.076426 155 176 6 2.251629 2.251629 2.251629 1.942129 0.309500 6.037606e+00 1.798008 -7.030826 127 135 6 2.251629 2.251629 2.251629 1.942629 0.309000 6.935891e+00 1.936709 -6.897647 268 284 6 2.251629 2.251629 2.251629 1.942629 0.309000 6.935891e+00 1.936709 -6.897647 66 212 6 2.251629 2.251629 2.251629 1.942796 0.308833 7.255271e+00 1.981728 -6.854421 156 266 6 2.251629 2.251629 2.251629 1.942963 0.308667 7.584901e+00 2.026160 -6.811759 213 246 6 2.251629 2.251629 2.251629 1.942963 0.308667 7.584901e+00 2.026160 -6.811759 82 109 6 2.251629 2.251629 2.251629 1.943963 0.307667 9.786922e+00 2.281047 -6.567021 217 283 6 2.251629 2.251629 2.251629 1.943963 0.307667 9.786922e+00 2.281047 -6.567021 234 283 6 2.251629 2.251629 2.251629 1.944129 0.307500 1.019276e+01 2.321678 -6.528009 162 194 6 1.918296 1.918296 1.918296 1.334963 0.583333 1.041989e+01 2.343716 -6.506847 72 215 6 1.918296 1.918296 1.918296 1.336296 0.582000 1.205408e+01 2.489403 -6.366962 112 169 6 1.918296 1.918296 1.918296 1.339129 0.579167 1.236278e+01 2.514690 -6.342682 53 249 6 1.918296 1.918296 1.918296 1.335296 0.583000 1.259487e+01 2.533289 -6.324823 219 272 6 1.918296 1.918296 1.918296 1.340129 0.578167 1.363313e+01 2.612503 -6.248764 42 234 6 2.251629 2.251629 2.251629 1.945629 0.306000 1.438016e+01 2.665850 -6.197541 65 143 7 2.521641 2.235926 2.235926 1.974069 0.261857 1.490669e+01 2.701810 -6.163013 72 146 7 2.235926 2.521641 2.235926 1.974212 0.261714 1.544231e+01 2.737111 -6.129118 153 167 7 2.235926 2.521641 2.235926 1.974355 0.261571 1.599074e+01 2.772010 -6.095609 96 110 7 2.128085 2.128085 2.128085 1.564620 0.563466 1.756718e+01 2.866033 -6.005330 236 277 7 2.521641 2.235926 2.235926 1.974783 0.261143 1.771420e+01 2.874366 -5.997328 165 227 6 1.918296 1.918296 1.918296 1.345629 0.572667 1.879963e+01 2.933837 -5.940226 118 139 7 1.950212 2.235926 1.950212 1.457355 0.492857 1.956296e+01 2.973638 -5.902010 69 169 6 1.918296 1.918296 1.918296 1.340129 0.578167 2.060644e+01 3.025604 -5.852113 254 281 7 2.235926 1.950212 1.950212 1.457212 0.493000 2.143354e+01 3.064957 -5.814327 85 139 7 2.521641 2.235926 2.235926 1.975641 0.260286 2.152314e+01 3.069128 -5.810322 57 163 7 2.128085 2.128085 2.128085 1.563873 0.564212 2.215729e+01 3.098166 -5.782440 236 254 7 2.521641 2.235926 2.235926 1.975783 0.260143 2.220617e+01 3.100370 -5.780324 242 270 7 2.521641 2.235926 2.235926 1.975926 0.260000 2.290325e+01 3.131279 -5.750646 143 168 7 2.235926 2.521641 2.235926 1.976069 0.259857 2.361447e+01 3.161860 -5.721283 104 145 6 1.918296 1.918296 1.918296 1.345463 0.572833 2.381274e+01 3.170221 -5.713255 144 160 7 2.235926 2.521641 2.235926 1.976212 0.259714 2.433994e+01 3.192119 -5.692229 254 268 7 2.235926 2.521641 2.235926 1.976212 0.259714 2.433994e+01 3.192119 -5.692229 66 176 7 2.521641 2.235926 2.235926 1.976355 0.259571 2.507974e+01 3.222060 -5.663480 234 242 7 2.235926 2.521641 2.235926 1.976355 0.259571 2.507974e+01 3.222060 -5.663480 236 270 7 2.521641 2.235926 2.235926 1.976355 0.259571 2.507974e+01 3.222060 -5.663480 80 89 7 2.235926 2.521641 2.235926 1.976498 0.259429 2.583397e+01 3.251690 -5.635029 92 124 7 2.521641 2.235926 2.235926 1.976641 0.259286 2.660272e+01 3.281013 -5.606874 262 277 7 2.521641 2.235926 2.235926 1.976783 0.259143 2.738607e+01 3.310034 -5.579009 146 176 7 2.521641 2.235926 2.235926 1.976926 0.259000 2.818411e+01 3.338758 -5.551429 246 280 7 2.235926 2.521641 2.235926 1.976926 0.259000 2.818411e+01 3.338758 -5.551429 52 179 7 1.148835 1.556657 0.863121 0.520469 0.342652 2.855970e+01 3.351997 -5.538717 86 168 7 2.235926 2.521641 2.235926 1.977069 0.258857 2.899691e+01 3.367189 -5.524130 143 151 7 2.235926 2.521641 2.235926 1.977069 0.258857 2.899691e+01 3.367189 -5.524130 254 262 7 2.235926 2.521641 2.235926 1.977069 0.258857 2.899691e+01 3.367189 -5.524130 268 277 7 2.521641 2.235926 2.235926 1.977069 0.258857 2.899691e+01 3.367189 -5.524130 246 269 7 2.235926 1.950212 1.950212 1.464926 0.485286 2.932636e+01 3.378487 -5.513282 125 153 7 2.521641 2.235926 2.235926 1.977212 0.258714 2.982457e+01 3.395332 -5.497107 242 277 7 2.521641 2.235926 2.235926 1.977212 0.258714 2.982457e+01 3.395332 -5.497107 47 174 7 1.378783 1.378783 1.378783 0.536069 0.842714 3.013305e+01 3.405623 -5.487227 93 147 7 2.235926 2.521641 2.235926 1.977498 0.258429 3.152473e+01 3.450772 -5.443875 139 168 7 2.235926 2.521641 2.235926 1.977641 0.258286 3.239739e+01 3.478078 -5.417657 73 153 7 2.521641 2.235926 2.235926 1.977926 0.258000 3.418822e+01 3.531881 -5.365996 121 168 7 2.235926 2.521641 2.235926 1.977926 0.258000 3.418822e+01 3.531881 -5.365996 143 175 7 2.235926 2.521641 2.235926 1.977926 0.258000 3.418822e+01 3.531881 -5.365996 242 254 7 2.521641 2.235926 2.235926 1.977926 0.258000 3.418822e+01 3.531881 -5.365996 72 158 7 2.235926 2.521641 2.235926 1.978069 0.257857 3.510653e+01 3.558387 -5.340546 234 262 7 2.235926 2.521641 2.235926 1.978069 0.257857 3.510653e+01 3.558387 -5.340546 42 112 7 2.128085 1.842371 1.842371 1.317760 0.524611 3.528399e+01 3.563429 -5.335704 45 91 7 1.378783 1.378783 1.378783 0.535719 0.843064 3.610937e+01 3.586552 -5.313502 65 109 7 2.521641 2.235926 2.235926 1.978355 0.257571 3.698924e+01 3.610627 -5.290386 66 127 7 2.521641 2.235926 2.235926 1.978498 0.257429 3.795377e+01 3.636369 -5.265669 233 254 7 1.950212 2.235926 1.950212 1.466498 0.483714 3.878691e+01 3.658083 -5.244820 65 120 7 2.521641 2.235926 2.235926 1.978641 0.257286 3.893383e+01 3.661864 -5.241190 238 270 7 1.842371 2.235926 1.842371 1.372800 0.469571 3.923723e+01 3.669626 -5.233736 73 156 7 2.521641 2.235926 2.235926 1.978926 0.257000 4.094075e+01 3.712126 -5.192929 120 175 7 2.235926 2.521641 2.235926 1.978926 0.257000 4.094075e+01 3.712126 -5.192929 226 243 7 1.842371 2.128085 1.842371 1.319708 0.522663 4.222593e+01 3.743034 -5.163251 263 277 7 1.842371 2.235926 1.842371 1.373085 0.469286 4.369901e+01 3.777326 -5.130325 73 161 7 2.521641 2.235926 2.235926 1.979355 0.256571 4.406893e+01 3.785755 -5.122232 109 151 7 2.235926 2.521641 2.235926 1.979355 0.256571 4.406893e+01 3.785755 -5.122232 42 140 7 2.128085 1.842371 1.842371 1.316353 0.526018 4.437550e+01 3.792688 -5.115575 109 125 7 2.235926 2.521641 2.235926 1.979783 0.256143 4.733960e+01 3.857347 -5.053490 124 147 7 2.235926 2.521641 2.235926 1.979783 0.256143 4.733960e+01 3.857347 -5.053490 254 263 7 2.235926 1.842371 1.842371 1.375942 0.466429 4.786996e+01 3.868488 -5.042793 227 243 7 1.842371 2.128085 1.842371 1.318372 0.523999 4.829550e+01 3.877338 -5.034295 250 263 7 2.128085 1.842371 1.842371 1.320943 0.521428 4.958198e+01 3.903627 -5.009053 89 164 7 2.521641 2.235926 2.235926 1.980212 0.255714 5.075389e+01 3.926988 -4.986622 224 238 7 2.128085 1.842371 1.842371 1.322426 0.519945 5.132793e+01 3.938235 -4.975824 68 78 7 1.842371 1.556657 1.556657 0.863404 0.693253 5.139904e+01 3.939620 -4.974494 148 162 7 2.128085 1.842371 1.842371 1.319302 0.523069 5.285795e+01 3.967608 -4.947620 109 167 7 2.235926 2.521641 2.235926 1.980783 0.255143 5.553134e+01 4.016948 -4.900245 127 146 7 2.235926 2.521641 2.235926 1.980783 0.255143 5.553134e+01 4.016948 -4.900245 254 272 7 2.235926 1.842371 1.842371 1.375514 0.466857 5.735486e+01 4.049258 -4.869222 109 175 7 2.235926 2.521641 2.235926 1.981069 0.254857 5.801706e+01 4.060737 -4.858200 227 237 7 1.842371 2.128085 1.842371 1.323463 0.518908 5.832287e+01 4.065994 -4.853152 90 112 7 2.235926 1.842371 1.842371 1.382514 0.459857 5.884899e+01 4.074975 -4.844529 226 237 7 1.842371 2.128085 1.842371 1.325035 0.517336 5.913328e+01 4.079794 -4.839902 164 254 6 1.918296 2.251629 1.918296 1.620050 0.298246 5.943571e+01 4.084895 -4.835003 98 119 7 1.842371 2.235926 1.842371 1.379800 0.462571 5.952442e+01 4.086387 -4.833571 79 98 7 2.235926 1.842371 1.842371 1.381085 0.461286 5.994643e+01 4.093451 -4.826788 41 72 7 1.842371 2.235926 1.842371 1.378228 0.464143 6.028330e+01 4.099055 -4.821407 229 273 7 2.235926 1.842371 1.842371 1.378371 0.464000 6.052660e+01 4.103083 -4.817540 238 254 7 1.842371 2.235926 1.842371 1.382514 0.459857 6.057119e+01 4.103819 -4.816833 219 268 6 1.918296 2.251629 1.918296 1.620193 0.298103 6.095086e+01 4.110068 -4.810833 98 110 7 1.842371 2.128085 1.842371 1.326946 0.515425 6.123431e+01 4.114708 -4.806378 68 153 7 1.842371 2.235926 1.842371 1.379942 0.462429 6.148073e+01 4.118724 -4.802522 68 107 7 1.842371 2.128085 1.842371 1.328232 0.514139 6.185590e+01 4.124807 -4.796681 85 93 7 2.521641 2.235926 2.235926 1.981498 0.254429 6.186745e+01 4.124994 -4.796501 262 270 7 2.521641 2.235926 2.235926 1.981641 0.254286 6.318347e+01 4.146043 -4.776291 105 165 7 1.842371 2.235926 1.842371 1.382085 0.460286 6.336613e+01 4.148929 -4.773519 120 151 7 2.235926 2.521641 2.235926 1.981783 0.254143 6.451580e+01 4.166910 -4.756254 68 161 7 1.842371 2.235926 1.842371 1.381085 0.461286 6.885328e+01 4.231978 -4.693778 234 263 7 2.235926 1.842371 1.842371 1.380942 0.461429 6.951846e+01 4.241592 -4.684546 234 268 7 2.235926 2.521641 2.235926 1.982783 0.253143 7.429981e+01 4.308108 -4.620679 69 112 7 2.235926 1.842371 1.842371 1.383942 0.458429 7.702985e+01 4.344193 -4.586031 78 107 7 1.556657 2.128085 1.556657 1.082143 0.474514 7.972749e+01 4.378615 -4.552980 263 283 6 1.918296 2.251629 1.918296 1.622963 0.295333 8.278703e+01 4.416271 -4.516823 219 245 6 1.918296 2.251629 1.918296 1.623296 0.295000 8.595623e+01 4.453838 -4.480752 238 285 6 1.459148 1.459148 1.459148 0.678042 0.781106 8.886528e+01 4.487121 -4.448794 93 270 6 1.918296 2.251629 1.918296 1.623629 0.294667 8.919201e+01 4.490791 -4.445270 43 60 6 1.000000 1.792481 1.000000 0.584930 0.415070 9.217465e+01 4.523685 -4.413687 99 180 6 1.459148 1.459148 1.459148 0.680671 0.778476 9.289366e+01 4.531455 -4.406226 44 64 7 0.863121 1.148835 0.863121 0.288306 0.574814 9.443525e+01 4.547914 -4.390422 185 265 6 1.251629 0.918296 0.918296 0.363456 0.554840 9.754334e+01 4.580297 -4.359329 127 215 6 2.251629 1.918296 1.918296 1.624463 0.293833 9.757202e+01 4.580591 -4.359047 51 221 6 1.459148 1.459148 1.459148 0.675061 0.784087 9.905105e+01 4.595635 -4.344601 217 272 6 2.251629 1.918296 1.918296 1.624629 0.293667 9.929769e+01 4.598122 -4.342213 122 272 6 1.792481 1.792481 1.792481 1.180703 0.611779 9.930632e+01 4.598209 -4.342130 136 263 6 1.000000 1.792481 1.000000 0.585849 0.414151 9.970175e+01 4.602183 -4.338314 196 238 6 1.792481 1.792481 1.792481 1.181369 0.611112 9.980971e+01 4.603265 -4.337275