# file generated by correlated-columns # ReadA2M T0241.t04-thin35.a2m.gz # SetMinSep 7 # SetMinPairs 0.7 requires 9 occupied positions in both columns # resulting in 23200 column pairs to test # reporting E-value <= 100 # MutualInfoSignif T0241.t04-thin35.mi.constraints # # There are 237 columns and 12 sequences # mean and standard deviation of log(E_value) for pairs not reported: 9.14014 0.995696 # mean and standard deviation of log(E_value) for all pairs: 9.09694 1.12205 # found 166 significant column pairs col1 col2 occupation info1 info2 mut_info mean_rand corr_mut_info e_value log_e_value Z_score 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 10N 118 222 10 2.921928 3.121928 2.921928 2.730577 0.191351 5.125963e-02 -2.970852 -12.163337 201 212 11 2.663533 3.095795 2.663533 2.331078 0.332455 1.302422e-01 -2.038360 -11.226815 93 212 10 2.646439 3.121928 2.646439 2.456055 0.190385 1.772889e-01 -1.729974 -10.917097 41 212 10 2.921928 3.121928 2.921928 2.731728 0.190200 1.882237e-01 -1.670124 -10.856988 1 184 9 2.197160 2.419382 2.197160 1.565858 0.631302 4.409238e-01 -0.818883 -10.002068 78 116 10 2.846439 2.646439 2.646439 2.227581 0.418858 5.818671e-01 -0.541513 -9.723499 16 213 10 2.446439 2.446439 2.246439 1.680292 0.566147 5.849204e-01 -0.536279 -9.718242 87 169 10 2.721928 2.321928 2.321928 1.816328 0.505600 6.794879e-01 -0.386416 -9.567731 127 149 11 2.845351 2.845351 2.663533 2.282922 0.380611 7.908378e-01 -0.234662 -9.415322 90 103 9 2.725481 2.947703 2.725481 2.515925 0.209556 8.497295e-01 -0.162837 -9.343186 89 202 10 2.446439 2.846439 2.446439 2.035679 0.410760 9.472101e-01 -0.054234 -9.234114 99 118 10 3.121928 2.721928 2.721928 2.534056 0.187872 1.388047e+00 0.327898 -8.850330 99 121 10 3.121928 2.846439 2.846439 2.658739 0.187700 1.528427e+00 0.424239 -8.753572 143 222 10 2.846439 3.121928 2.846439 2.658839 0.187600 1.633149e+00 0.490510 -8.687015 105 217 11 2.550341 3.095795 2.550341 2.232068 0.318273 2.363189e+00 0.860012 -8.315916 1 22 10 2.446439 2.370951 2.170951 1.625633 0.545318 2.698189e+00 0.992581 -8.182774 40 201 10 2.170951 2.721928 2.170951 1.666629 0.504322 3.293994e+00 1.192101 -7.982391 23 30 11 2.481715 2.550341 2.186704 1.707530 0.479175 3.541812e+00 1.264638 -7.909540 4 80 11 2.118078 2.913977 2.118078 1.664722 0.453357 3.701747e+00 1.308805 -7.865183 82 198 10 2.370951 1.846439 1.846439 1.153165 0.693274 4.450582e+00 1.493035 -7.680157 127 165 11 2.845351 2.732159 2.481715 2.166805 0.314909 5.110142e+00 1.631227 -7.541367 98 122 10 2.446439 1.846439 1.846439 1.183121 0.663318 5.333477e+00 1.674003 -7.498406 167 182 11 2.049452 1.322179 1.322179 0.682118 0.640062 5.615638e+00 1.725555 -7.446631 38 72 11 0.684038 0.684038 0.684038 0.080225 0.603813 5.839485e+00 1.764643 -7.407375 14 161 9 0.991076 2.281036 0.991076 0.607655 0.383421 5.952320e+00 1.783781 -7.388154 78 170 10 2.846439 2.321928 2.321928 1.924105 0.397823 6.099415e+00 1.808193 -7.363636 66 148 10 3.121928 2.446439 2.446439 2.261193 0.185246 6.636305e+00 1.892555 -7.278909 146 212 11 2.368523 3.095795 2.368523 2.058251 0.310272 7.284627e+00 1.985766 -7.185296 12 105 11 2.481715 2.550341 2.186704 1.714396 0.472308 7.799295e+00 2.054033 -7.116733 26 84 11 2.663533 2.845351 2.481715 2.117832 0.363882 7.886124e+00 2.065105 -7.105614 110 206 11 1.971747 2.004886 1.676737 0.974865 0.701872 7.937588e+00 2.071609 -7.099081 1 201 9 2.197160 2.725481 2.197160 1.813826 0.383333 7.997282e+00 2.079102 -7.091557 57 195 10 2.846439 2.370951 2.370951 1.969481 0.401469 8.054267e+00 2.086202 -7.084426 63 85 11 2.913977 2.663533 2.481715 2.168358 0.313357 8.429549e+00 2.131743 -7.038688 85 192 10 2.646439 2.646439 2.446439 2.047472 0.398967 9.297605e+00 2.229757 -6.940250 89 204 10 2.446439 2.321928 2.121928 1.595668 0.526260 9.660252e+00 2.268020 -6.901822 1 141 9 2.197160 2.725481 2.197160 1.813938 0.383222 9.675076e+00 2.269553 -6.900282 99 219 9 2.947703 2.503258 2.503258 2.298481 0.204778 9.816475e+00 2.284062 -6.885710 5 138 9 1.891061 2.419382 1.891061 1.313126 0.577936 1.080107e+01 2.379645 -6.789715 118 143 11 2.913977 2.732159 2.550341 2.246886 0.303455 1.089564e+01 2.388362 -6.780959 127 170 11 2.845351 2.222192 2.222192 1.744755 0.477437 1.142637e+01 2.435923 -6.733193 111 170 11 1.617190 2.222192 1.617190 0.902503 0.714686 1.182195e+01 2.469958 -6.699011 75 222 9 2.419382 2.947703 2.419382 2.215475 0.203907 1.387978e+01 2.630433 -6.537842 93 184 10 2.646439 2.446439 2.246439 1.856417 0.390023 1.437484e+01 2.665479 -6.502645 11 202 10 2.170951 2.846439 2.170951 1.791321 0.379630 1.479066e+01 2.693996 -6.474005 61 107 10 2.646439 2.160964 2.160964 1.646637 0.514327 1.498263e+01 2.706892 -6.461053 14 120 9 0.991076 1.657743 0.991076 0.362846 0.628230 1.519525e+01 2.720983 -6.446901 73 210 10 1.685475 1.685475 1.409987 0.677942 0.732045 1.542170e+01 2.735776 -6.432044 63 138 9 2.947703 2.419382 2.419382 2.215901 0.203481 1.600600e+01 2.772964 -6.394696 1 93 10 2.446439 2.646439 2.246439 1.857355 0.389085 1.693209e+01 2.829211 -6.338206 23 193 10 2.446439 2.646439 2.246439 1.860288 0.386151 1.695057e+01 2.830301 -6.337110 81 111 10 2.160964 1.685475 1.685475 1.001709 0.683766 1.831066e+01 2.907483 -6.259595 81 116 10 2.160964 2.646439 2.160964 1.654752 0.506212 1.842921e+01 2.913937 -6.253113 31 124 10 2.321928 2.246439 1.921928 1.426893 0.495035 1.872359e+01 2.929784 -6.237197 58 122 10 2.046439 1.846439 1.570951 0.937891 0.633059 1.978870e+01 2.985111 -6.181631 52 89 11 2.845351 2.663533 2.413088 2.110892 0.302197 2.002122e+01 2.996793 -6.169899 129 143 11 2.222192 2.732159 2.222192 1.685999 0.536193 2.076935e+01 3.033478 -6.133055 20 136 9 2.058814 2.281036 2.058814 1.411354 0.647460 2.138029e+01 3.062470 -6.103939 202 220 10 2.921928 2.446439 2.446439 2.105579 0.340860 2.169608e+01 3.077131 -6.089213 78 114 10 2.846439 2.321928 2.321928 1.934179 0.387749 2.172155e+01 3.078305 -6.088035 121 168 11 2.845351 2.040373 2.040373 1.580097 0.460277 2.192902e+01 3.087811 -6.078488 40 213 10 2.170951 2.446439 1.970951 1.445090 0.525860 2.336821e+01 3.151377 -6.014647 76 192 10 1.960964 2.646439 1.960964 1.459837 0.501127 2.417275e+01 3.185226 -5.980651 110 149 11 1.971747 2.845351 1.971747 1.524412 0.447335 2.467474e+01 3.205780 -5.960009 15 102 10 2.321928 2.370951 2.046439 1.546146 0.500293 2.533239e+01 3.232084 -5.933591 41 49 11 2.845351 2.413088 2.231270 1.887745 0.343525 2.546475e+01 3.237295 -5.928357 26 58 11 2.663533 2.118078 1.936260 1.481653 0.454607 2.604990e+01 3.260014 -5.905540 88 163 10 2.446439 2.446439 2.170951 1.701279 0.469671 2.612534e+01 3.262906 -5.902636 99 220 9 2.947703 2.503258 2.503258 2.301592 0.201667 2.622502e+01 3.266714 -5.898812 138 168 10 2.646439 1.960964 1.960964 1.459606 0.501358 2.682960e+01 3.289506 -5.875921 87 148 10 2.721928 2.446439 2.246439 1.913106 0.333333 2.761602e+01 3.318396 -5.846906 1 180 9 2.197160 2.058814 1.836592 1.297494 0.539098 2.765804e+01 3.319917 -5.845379 94 220 9 2.419382 2.503258 2.197160 1.828049 0.369111 2.796269e+01 3.330871 -5.834377 15 140 10 2.321928 2.246439 1.921928 1.434570 0.487358 2.944258e+01 3.382442 -5.782583 69 184 10 2.121928 2.446439 1.921928 1.416717 0.505211 3.144871e+01 3.448358 -5.716382 127 180 11 2.845351 1.971747 1.971747 1.531613 0.440135 3.148030e+01 3.449362 -5.715374 66 99 11 3.095795 3.095795 2.913977 2.749072 0.164905 3.219499e+01 3.471811 -5.692828 103 114 10 3.121928 2.321928 2.321928 2.141046 0.180882 3.220566e+01 3.472142 -5.692495 64 79 11 2.231270 1.491115 1.309297 0.801156 0.508141 3.383290e+01 3.521434 -5.642990 2 12 11 2.550341 2.481715 2.118078 1.717278 0.400800 3.393529e+01 3.524455 -5.639956 52 165 10 2.646439 2.521928 2.246439 1.917039 0.329400 3.444862e+01 3.539469 -5.624877 184 191 11 2.663533 2.222192 2.040373 1.599661 0.440713 3.467426e+01 3.545998 -5.618320 16 150 10 2.446439 2.721928 2.246439 1.914109 0.332331 3.556268e+01 3.571297 -5.592912 9 97 11 1.789929 2.845351 1.789929 1.351695 0.438234 3.565905e+01 3.574003 -5.590194 71 114 10 2.370951 2.321928 2.046439 1.548348 0.498091 3.570027e+01 3.575158 -5.589034 40 180 10 2.170951 1.960964 1.685475 1.131342 0.554133 3.579910e+01 3.577923 -5.586257 1 8 10 2.446439 2.170951 1.970951 1.437611 0.533340 3.622049e+01 3.589625 -5.574505 22 184 10 2.046439 2.446439 1.846439 1.361440 0.484999 3.624626e+01 3.590336 -5.573790 103 199 10 3.121928 2.646439 2.646439 2.466192 0.180247 3.697199e+01 3.610161 -5.553880 59 206 10 2.321928 2.046439 1.846439 1.312734 0.533705 3.753488e+01 3.625271 -5.538705 140 210 11 2.231270 1.617190 1.435371 0.839405 0.595967 3.921503e+01 3.669060 -5.494726 13 169 10 2.170951 2.321928 1.846439 1.370979 0.475460 4.019465e+01 3.693734 -5.469946 80 149 10 2.921928 2.921928 2.721928 2.541120 0.180808 4.060249e+01 3.703829 -5.459806 34 193 10 1.960964 2.646439 1.960964 1.470503 0.490461 4.131244e+01 3.721164 -5.442397 68 128 10 2.446439 2.160964 1.960964 1.494890 0.466074 4.151283e+01 3.726002 -5.437538 77 118 10 2.521928 2.721928 2.321928 2.004128 0.317800 4.194365e+01 3.736327 -5.427168 22 40 11 2.299896 2.118078 1.754442 1.235378 0.519063 4.251626e+01 3.749887 -5.413550 96 204 10 1.360964 2.321928 1.360964 0.804359 0.556605 4.275898e+01 3.755579 -5.407833 52 209 10 2.646439 2.646439 2.370951 2.033579 0.337372 4.276700e+01 3.755767 -5.407645 4 103 11 2.118078 3.095795 2.118078 1.819351 0.298727 4.358129e+01 3.774628 -5.388702 58 66 11 2.118078 3.095795 2.118078 1.822260 0.295818 4.408909e+01 3.786212 -5.377067 101 196 10 2.646439 2.521928 2.246439 1.920469 0.325970 4.418481e+01 3.788381 -5.374889 18 196 10 2.646439 2.521928 2.246439 1.919239 0.327200 4.593946e+01 3.827324 -5.335778 91 205 10 2.646439 2.521928 2.246439 1.922039 0.324400 4.619932e+01 3.832965 -5.330113 167 220 10 2.160964 2.446439 1.960964 1.496818 0.464146 4.634315e+01 3.836074 -5.326991 86 207 10 1.846439 2.046439 1.570951 0.950215 0.620735 4.696120e+01 3.849322 -5.313685 127 178 11 2.845351 1.789929 1.789929 1.355764 0.434165 4.832851e+01 3.878022 -5.284861 11 89 11 2.118078 2.663533 1.936260 1.481478 0.454782 4.987144e+01 3.909449 -5.253299 82 98 11 2.299896 2.413088 1.867634 1.435977 0.431657 5.049528e+01 3.921880 -5.240814 203 214 11 2.186704 2.594907 1.936260 1.508101 0.428159 5.126025e+01 3.936916 -5.225713 20 163 10 2.046439 2.446439 1.846439 1.367521 0.478918 5.376472e+01 3.984618 -5.177805 63 103 11 2.913977 3.095795 2.732159 2.567657 0.164502 5.424307e+01 3.993475 -5.168909 22 180 10 2.046439 1.960964 1.685475 1.075558 0.609917 5.529059e+01 4.012603 -5.149699 66 138 9 2.947703 2.419382 2.419382 2.220729 0.198653 5.563518e+01 4.018816 -5.143459 23 83 11 2.481715 3.277613 2.481715 2.319533 0.162182 5.625132e+01 4.029830 -5.132397 11 204 10 2.170951 2.321928 1.846439 1.377206 0.469233 5.656436e+01 4.035379 -5.126824 9 216 10 1.846439 1.356780 1.156780 0.657933 0.498847 5.712734e+01 4.045283 -5.116877 14 77 10 0.970951 2.521928 0.970951 0.639827 0.331124 5.819221e+01 4.063752 -5.098329 148 208 11 2.413088 2.481715 1.980826 1.573348 0.407478 5.886819e+01 4.075301 -5.086729 80 107 10 2.921928 2.160964 2.160964 1.847264 0.313700 5.955534e+01 4.086906 -5.075074 197 223 9 2.947703 2.419382 2.419382 2.221604 0.197778 6.426242e+01 4.162975 -4.998676 73 140 10 1.685475 2.246439 1.485475 0.934656 0.550819 6.503919e+01 4.174990 -4.986609 180 213 11 1.971747 2.663533 1.789929 1.373642 0.416287 6.509502e+01 4.175848 -4.985748 184 222 10 2.446439 3.121928 2.446439 2.268639 0.177800 6.547029e+01 4.181596 -4.979974 59 222 9 2.419382 2.947703 2.419382 2.221715 0.197667 6.565199e+01 4.184368 -4.977191 61 196 10 2.646439 2.521928 2.246439 1.930076 0.316364 6.709413e+01 4.206097 -4.955368 91 179 10 2.646439 1.760964 1.760964 1.284789 0.476175 6.746154e+01 4.211558 -4.949884 95 179 10 1.846439 1.760964 1.360964 0.757455 0.603509 7.177413e+01 4.273524 -4.887649 5 66 11 1.823068 3.095795 1.823068 1.538977 0.284091 7.202871e+01 4.277065 -4.884093 41 93 11 2.845351 2.845351 2.594907 2.289181 0.305725 7.242649e+01 4.282572 -4.878562 33 98 11 1.685816 2.413088 1.503998 1.000999 0.502998 7.403152e+01 4.304491 -4.856549 13 204 10 2.170951 2.321928 1.846439 1.377968 0.468471 7.503273e+01 4.317924 -4.843057 39 193 10 2.321928 2.646439 2.121928 1.754639 0.367289 7.538743e+01 4.322641 -4.838321 60 170 10 1.770951 2.321928 1.770951 1.159989 0.610961 7.563039e+01 4.325858 -4.835089 7 38 11 0.865857 0.684038 0.684038 0.139781 0.544257 7.584788e+01 4.328730 -4.832205 62 80 11 2.413088 2.913977 2.231270 1.941455 0.289815 7.616773e+01 4.332938 -4.827979 137 199 10 1.721928 2.721928 1.721928 1.290171 0.431757 7.716498e+01 4.345946 -4.814915 100 219 9 1.657743 2.503258 1.657743 1.199187 0.458556 7.779339e+01 4.354056 -4.806769 67 84 11 2.368523 2.845351 2.186704 1.859682 0.327023 7.792691e+01 4.355771 -4.805047 80 160 10 2.921928 2.170951 2.170951 1.847057 0.323894 8.007567e+01 4.382972 -4.777728 30 39 11 2.550341 2.222192 2.040373 1.550314 0.490060 8.107425e+01 4.395365 -4.765282 18 82 11 2.663533 2.299896 2.049452 1.655262 0.394190 8.145585e+01 4.400061 -4.760566 14 194 9 0.991076 2.058814 0.991076 0.483498 0.507578 8.172422e+01 4.403350 -4.757262 171 222 10 2.446439 3.121928 2.446439 2.269679 0.176761 8.188851e+01 4.405359 -4.755245 27 97 11 1.867634 2.845351 1.867634 1.452946 0.414688 8.278313e+01 4.416224 -4.744333 161 194 11 2.222192 2.040373 1.712224 1.166390 0.545834 8.297354e+01 4.418522 -4.742025 79 114 10 1.570951 2.321928 1.570951 0.990385 0.580565 8.356082e+01 4.425575 -4.734942 209 223 9 2.419382 2.419382 2.113283 1.769311 0.343972 8.422640e+01 4.433508 -4.726974 65 217 10 2.370951 3.121928 2.370951 2.194451 0.176500 8.555511e+01 4.449161 -4.711254 106 194 11 2.231270 2.040373 1.608111 1.119657 0.488454 8.634360e+01 4.458335 -4.702040 53 184 10 2.046439 2.446439 1.846439 1.365447 0.480992 8.706635e+01 4.466670 -4.693668 4 75 11 2.118078 2.594907 1.867634 1.448387 0.419247 9.027138e+01 4.502820 -4.657362 28 92 11 1.617190 2.231270 1.366745 0.841427 0.525319 9.042049e+01 4.504471 -4.655704 10 72 11 0.865857 0.684038 0.684038 0.140155 0.543884 9.230078e+01 4.525053 -4.635034 10 38 11 0.865857 0.684038 0.684038 0.133735 0.550304 9.230639e+01 4.525113 -4.634973 100 204 10 1.570951 2.321928 1.570951 0.991870 0.579080 9.267185e+01 4.529065 -4.631004 13 55 11 2.118078 2.550341 1.823068 1.420396 0.402672 9.421343e+01 4.545563 -4.614435 12 217 10 2.246439 3.121928 2.246439 2.070202 0.176238 9.421694e+01 4.545600 -4.614398 3 36 11 1.789929 1.240671 0.990226 0.454031 0.536195 9.477471e+01 4.551503 -4.608469 3 145 10 1.760964 2.321928 1.560964 1.051970 0.508994 9.645719e+01 4.569099 -4.590797 7 72 11 0.865857 0.684038 0.684038 0.139499 0.544539 9.670659e+01 4.571682 -4.588203 26 116 10 2.446439 2.646439 2.170951 1.854582 0.316369 9.693079e+01 4.573997 -4.585878 199 214 11 2.663533 2.594907 2.231270 1.900974 0.330296 9.773738e+01 4.582284 -4.577555 99 195 10 3.121928 2.370951 2.370951 2.195137 0.175814 9.784410e+01 4.583375 -4.576459 78 198 10 2.846439 1.846439 1.846439 1.499489 0.346950 9.948300e+01 4.599987 -4.559776 50 78 11 1.672933 2.845351 1.672933 1.286425 0.386508 9.985270e+01 4.603696 -4.556050