(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • YDL116W NUP84 SGDID:S0002274, Chr IV from 251565-253745
    • gi|6320087|ref|NP_010167.1|_1:726 (NC_001136) component of nuclear pores; Part of complex with Nup120p, Nup85p, Sec13p, and a Sec13p homolog; Nup84p [Saccharomyces cerevisiae]
    • gi|1709399sp|P52891|NU84_YEAST NUCLEOPORIN NUP84 (NUCLEAR PORE PROTEIN NUP84)
    • gi|2132367|pir||S62180 nuclear pore protein NUP84 - yeast (Saccharomyces cerevisiae)
    • gi|1177642|emb|CAA62479.1| (X90993) Nup84p [Saccharomyces cerevisiae]
    • gi|1431170|emb|CAA98684.1| (Z74164) ORF YDL116w [Saccharomyces cerevisiae]
    • gi|13435556|gb|AAH04655.1|_75:770 (BC004655) Unknown (protein for IMAGE:3497824) [Mus musculus]
    • gi|20865484|ref|XP_125866.1|_67:762 (XM_125866) similar to nuclear pore complex protein [Rattus norvegicus] [Mus musculus]
    • gi|16758682|ref|NP_446282.1|_219:914 (NM_053830) nuclear pore complex protein [Rattus norvegicus]
    • gi|1709212sp|P52590|N107_RAT NUCLEAR PORE COMPLEX PROTEIN NUP107 (NUCLEOPORIN NUP107) (107 KD NUCLEOPORIN) (P105)
    • gi|1083740|pir||A54142 nucleoporin NUP107 - rat
    • gi|510717|gb|AAA74476.1| (L31840) nuclear pore complex protein NUP107 [Rattus norvegicus]
    • gi|9966881|ref|NP_065134.1|_218:913 (NM_020401) nuclear pore complex protein [Homo sapiens]
    • gi|12230339sp|P57740|N107_HUMAN Nuclear pore complex protein Nup107 (Nucleoporin Nup107) (107 kDa nucleoporin)
    • gi|9843752|emb|CAC03716.1| (AJ295745) nuclear pore complex protein [Homo sapiens]
    • gi|19111971|ref|NP_595179.1|_92:769 (NC_003423) putative nuclear pore complex protein; nucleoporin [Schizosaccharomyces pombe]
    • gi|19862949sp|Q10331|YBMB_SCHPO Hypothetical protein C582.11c in chromosome II
    • gi|6723901|emb|CAB46674.2| (AL096788) putative nuclear pore complex protein; nucleoporin [Schizosaccharomyces pombe]
    • gi|21288528|gb|EAA00821.1|_213:909 (AAAB01008987) agCP12701 [Anopheles gambiae str. PEST]
    • gi|19921114|ref|NP_609446.1|_129:833 (NM_135602) BcDNA:LD18761 gene product [Drosophila melanogaster]
    • gi|5679144|gb|AAD46878.1|AF160938_1 (AF160938) BcDNA.LD18761 [Drosophila melanogaster]
    • gi|7297751|gb|AAF53002.1| (AE003629) CG6743-PA [Drosophila melanogaster]
    • gi|7492762|pir||T37972_2:489 probable nuclear pore complex protein - fission yeast (Schizosaccharomyces pombe) (fragment)
    • gi|1216241|emb|CAA93783.1| (Z69909) putative nuclear pore complex protein [Schizosaccharomyces pombe]
    • gi|9294637|dbj|BAB02976.1|_229:662 (AP000600) gene_id:MAG2.8~similar to unknown protein~sp|P52590 [Arabidopsis thaliana]
    • gi|22654979|gb|AAM98082.1|_248:627 (AY139761) AT3g14120/MAG2_7 [Arabidopsis thaliana]
    • gi|15231787|ref|NP_188028.1|_248:605 (NM_112268) hypothetical protein; protein id: At3g14120.1 [Arabidopsis thaliana]
    • gi|7522373|pir||T40453_92:280 hypothetical protein SPBC428.01c - fission yeast (Schizosaccharomyces pombe) (fragment)
    • gi|3947865|emb|CAA22276.1| (AL034382) putative nuclear pore protein; nucleoporin; similar to S. cerevisiae NUP84 [Schizosaccharomyces pombe] 
              10        20        30        40        50        60     
              |         |         |         |         |         |     
   1 MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRSAAGQLALDLANSGDESNVISS
   2 MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRSAAGQLALDLANSGDESNVISS
   3 -----------TWRLLASLYRDRIQSSLEEENMFAI-----------------AGINASEKMVVE
   4 -----------TWRLLASLYRDRIQSSLEEENMFAI-----------------AGINASEKMVVE
   5 -----------TWRLLASLYRDRIQSSLEEENMFAI-----------------AGINASEKTVVE
   6 -----------TWRLLASLYRDRIQSALEEESVFAVTAVNA-----------------SEKTVVE
   7 WDLE-----SRTWDLIQRLYSFRLSE--QQGHIQSH----AFSSRAVL-----------EEEYYS
   8 WDLE-----SRTWDLIQRLYSFRLSE--QQGHIQSH----AFSSRAVL-----------EEEYYS
   9 ----------DTWRLMICLYRDRLITQKQDSEMDDLPLVNS------------------EQTIIS
  10 ----------NTWRLLHALFYDRILLQTDRQADD--------------EMQDGPTLGGSEKEVIQ
  11 -----------------------------------------------------------------
  12 ------------------------------------------------------------EELAS
  13 ------------------------------------------------------------EELAS
  14 ------------------------------------------------------------EELAS
  15 WDLE-----SRTWDLIQRLYSFRLSE--QQGHIQSH----AFSSRAVL-----------EEEYYS


         70        80        90         100       110       120       1
         |         |         |           |         |         |        
   1 KDWELEARFWHLVELLLVFRNADLD..LDEMELHPYNSRGLFEKKLMQDNKQLYQIWIVMVWLKE
   2 KDWELEARFWHLVELLLVFRNADLD..LDEMELHPYNSRGLFEKKLMQDNKQLYQIWIVMVWLKE
   3 TLFQRDSLVRQSQLVVDWLESIAKD..----EIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSH-
   4 TLFQRDSLVRQSQLVVDWLESIAKD..----EIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSH-
   5 ALFQRDSLVRQSQLVVDWLESIAKDeiGDFSDNIEFYAKSVYWE------NTLHSLKQRQLLS--
   6 ALFQRDSLVRQSQLVVDWLESIAKD..----EIGEFSDNIEFYAKSVYWENTLHTLKQRQLTS--
   7 QNPEA-------FENNIVFNWA---..RDNSSDPPSIE--------IRGNRWFY-----------
   8 QNPEA-------FENNIVFNWA---..RDNSSDPPSIE--------IRGNRWFY-----------
   9 HLYGGNANLREYQIIVDWLEQMALR..QQQTELGHYMNRTVAWE------NTLHQLLEVGQTA--
  10 QLYALNATLREYQLVVDWLEACYDR..GEQQNPLHAHDRMMAWE------NTLFQLENLQGAA--
  11 -------------------------..--------------------------------------
  12 KSLDLERKMNGNLRNCMENTSKTLL..LLKSESGVYVPTFLVLRVLVQGSHVGTYLPNAGVWHHT
  13 KSLDLERK-----------------..-------------------VQGSHVGTYLPNAGVWHHT
  14 KSLDLERK-----------------..---------------------GSHVGTYLPNAGVWHHT
  15 QNPEA-------FENNIVFNWA---..RDNSSDPPSIE--------IRGNRWFY-----------


      30       140       150       160       170       180       190   
      |         |         |         |         |         |         |   
   1 NTYVMERPKNVPTSKWLNSITSGGLKSCDLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAI
   2 NTYVMERPKNVPTSKWLNSITSGGLKSCDLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAI
   3 -----------------MGSTRPLVTELDPDAPIRQKLP-LDDLDREDEVRLLKYLFTLIRAGMT
   4 -----------------MGSTRPLVTELDPDAPIRQKLP-LDDLDREDEVRLLKYLFTLIRAGMT
   5 ----------------YIGSTRPLVTELDPDAPIRQKMP-LDDLDREDEVRLLKYLFTLIRAGMT
   6 ----------------YVGSVRPLVTELDPDAPIRQKMP-LDDLDREDEVRLLKYLFTLIRAGMT
   7 -TREDIKMKNRGGSRFSSNISGTIVSNLDPDADIRDDKR-LDERDDNFERQFFHTAFCLFRSGSF
   8 -TREDIKMKNRGGSRFSSNISGTIVSNLDPDADIRDDKR-LDERDDNFERQFFHTAFCLFRSGSF
   9 -----------------FGSGRALVKGLDPDAPIREKLP-LHDLDMEDQTQLAKQVFRAIRQGRL
  10 -----------------FGKGHKIVTRLDPDAPVREKRP-LHALDEEDNLRLSRAIFELIRAGRV
  11 -----------------------------------------------------------------
  12 QRYLKK-----------NGSNADTLHHLDFDAPTREHARLLPD-DYKQDESVLEDVWTLIRAGRI
  13 QRYLKK-----------NGSNADTLHHLDFDAPTREHARLLPD-DYKQDESVLEDVWTLIRAGRI
  14 QRYLKK-----------NGSNADTLHHLDFDAPTREHARLLPD-DYKQDESVLEDVWTLIRAGRI
  15 -TREDIKMKNRGGSRFSSNISGTIVSNLDPDADIRDDKR-LDERDDNFERQFFHTAFCLFRSGSF


          200       210        220        230         240            25
           |         |          |          |           |              
   1 DEALEEAKLSDNISICMILCGIQEY.LNPVIDT.QIANEFN..TQQGIKKHS.....LWRRTVYS
   2 DEALEEAKLSDNISICMILCGIQEY.LNPVIDT.QIANEFN..TQQGIKKHS.....LWRRTVYS
   3 EEAQRLCKRCGQAWRAATLEGWKLY.HDPNVNG.--GTELE..PVEGNPYRR.....IWKISCWR
   4 EEAQRLCKRCGQAWRAATLEGWKLY.HDPNVNG.--GTELE..PVEGNPYRR.....IWKISCWR
   5 EEAQRLCKRCGQAWRAATLEGWKLH.HDPNVNG.--GTELE..PVEGNPYRR.....IWKISCWR
   6 EEAQRLCKRCGQAWRAATLEGWKLY.HDPNVNG.--GTELE..PVEGNPYRR.....IWKISCWR
   7 EELLELCRRTGNHWRSASLQGILEY.RDNLIDD.VLQSETS..---GNKRKE.....LLRRSCLA
   8 EELLELCRRTGNHWRSASLQGILEY.RDNLIDD.VLQSETS..---GNKRKE.....LLRRSCLA
   9 KEAQIKCENYGQAWKAALLEGWRLH.HDPNYDReNVSLARE..PIEGNPRRD.....LWKKFAWQ
  10 DDGLKLCKHFGQTWRAAILEGWRLH.EDPNFEQ.NVSVLHEklPIEGNPRRD.....IWKRCAWM
  11 -------------------------.-------.-------..---------.....-----CLA
  12 EEACDLCRSAGQSWRAATLCPFSGMdMFPSIEA.LVKNGENr.TLQAIEQESgf7lrLWKWASYC
  13 EEACDLCRSAGQSWRAATLCPFSGMdMFPSIEA.LVKNGENr.TLQAIEQESgf7lrLWKWASYC
  14 EEACDLCRSAGQSWRAATLCPFSGMdMFPSIEA.LVKNGENr.TLQAIEQESgf7lrLWKWASYC
  15 EELLELCRRTGNHWRSASLQGILEY.RDNLIDD.VLQSETS..---GNKRKE.....LLRR----


      0          260       270       280         290       300         
     |            |         |         |           |         |         
   1 LSQ...QAGLDPYERAIYSYLSGAIPNQEVLQYSD..WESDLHIHLNQILQTEIENYLL....EN
   2 LSQ...QAGLDPYERAIYSYLSGAIPNQEVLQYSD..WESDLHIHLNQILQTEIENYLL....EN
   3 MAE...DELFNKYERAIYAALSGNL-KQLLPVCDT..WEDTVWAYFRVMVDSLVEQEIR....TS
   4 MAE...DELFNKYERAIYAALSGNL-KQLLPVCDT..WEDTVWAYFRVMVDSLVEQEIR....TS
   5 MAE...DELFNKYERAIYAALSGNL-KQLLPVCDT..WEDTVWAYFRVMVDSLVEQEIR....TS
   6 MAE...DELFNRYERAIYAALSGNL-KQLLPVCDT..WEDTVWAYFRVMVDSLVEQEIQ....TS
   7 LTK...NKRIDSYERALYGALCGDL-NSVLDVCTT..WEDAMWAYYNSMTQYNLDVYL-....SS
   8 LTK...NKRIDSYERALYGALCGDL-NSVLDVCTT..WEDAMWAYYNSMTQYNLDVYL-....SS
   9 MAE...SRMLDPYTKATIGSLCGHL-DSMVEVLSEhsWNDMLWAYLKAQIDIRVESEIRshcvKS
  10 LAD...SKNYDEYSRATAGVFSGHLGSLKTLLHSN..WHDLLWAHLKVQIDIRVESEIRgcclKN
  11 LTK...NKRIDSYERALYGALCGDL-NSVLDVCTT..WEDAMWAYYNSMTQYNLDVYL-....SS
  12 ASEkiaEQDGGKHEVAVFATQCSNL-NRMLPICTD..WESACWAMAKSWLDVQVDLELA....QS
  13 ASEkiaEQDGGKHEVAVFATQCSNL-NRMLPICTD..WESACWAMAKSWLDVQVDLELA....QS
  14 ASEkiaEQDGGKHEVAVFATQCSNL-NRMLPICTD..WESACWAMAKSWLDVQVDLELA....QS
  15 ---...-----------------------------..----------------------....--


        310       320         330           340       350       360    
         |         |           |             |         |         |    
   1 NQVGTDELILPLPSH..ALTVQEVLNRVA....SRHPSESEHPIRVLMASVILDSLPSVIHSSVE
   2 NQVGTDELILPLPSH..ALTVQEVLNRVA....SRHPSESEHPIRVLMASVILDSLPSVIHSSVE
   3 VMTQDDSEELPREYMeaNWTLEKVFEELQatdkKRVLEENQEHYHIVQKFLILGDVDGLMDEFSK
   4 VMTQDDSEELPREYMeaNWTLEKVFEELQatdkKRVLEENQEHYHIVQKFLILGDVDGLMDEFSK
   5 VMTLDETEELPREYMeaNWTLEKVFEELQatdkKRVLEENQEHYHVVQKFLILGDIDGLMDEFSK
   6 VATLDETEELPREYLgaNWTLEKVFEELQatdkKRVLEENQEHYHIVQKFLILGDIDGLMDEFSK
   7 KAPQTETQLPPVDSGl.GLTPELIFNSLSnssiASIQEEASHPLIKLQTHIICNKISEIL-SSAH
   8 KAPQTETQLPPVDSGl.GLTPELIFNSLSnssiASIQEEASHPLIKLQTHIICNKISEIL-SSAH
   9 YLPMPDRYWNG----..KMSLEQIFDALEahknARISLAAKDVDKVIQKYIMLDDIPELMRTVDG
  10 YQPMPDDYWNG----..RMTMEQIFEELNvakdASVRDFAQSQLGIIQRHLILDTCGELI---QH
  11 KAPQTETQLPPVDSGl.GLTPELIFNSLSnssiASIQEEASHPLIKLQTHIICNKISEIL-SSAH
  12 KPGLTERFKSCIDE-..--SPEATQNGCQ....ASFGPE-DWPLHVL------------------
  13 KPGLTERFKSCIDE-..--SPEATQNGCQ....ASFGPE-DWPLHVL------------------
  14 KPGLTERFKSCIDE-..--SPEATQNGCQ....ASFGPE-DWPLHVL------------------
  15 ---------------..------------....--------------------------------


         370         380       390       400       410       420       
          |           |         |         |         |         |       
   1 MLLDVVKGTEA..SNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYE
   2 MLLDVVKGTEA..SNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYE
   3 WLSKSGSSL--..------PGHLLRFMTHLILFLRTLGLQTKEEV-SIEVLKTYIQLLISEKHTS
   4 WLSKSGSSL--..------PGHLLRFMTHLILFLRTLGLQTKEEV-SIEVLKTYIQLLISEKHTS
   5 WLSKSRSSL--..------PGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLINEKHTN
   6 WLSKSRNNL--..------PGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLIREKHTN
   7 IQLEAIRTGNApeSGDLVTPP-LLRILTHIILFLKISGL-AVDEYTSDSIIQAYIELLASAKKVN
   8 IQLEAIRTGNApeSGDLVTPP-LLRILTHIILFLKISGL-AVDEYTSDSIIQAYIELLASAKKVN
   9 WL--------E..GTEVVLIPQMLRFLTHFVMFLRQIGK-TFQEDIGDRVVKRYVEYLSTLGSAH
  10 MVRWVEKDTSQ..Q-----SPHQLRFMAHIVLFLRQIGR-VEQERQAEKIVAAYVEALIARGEPQ
  11 IQLEAIRTGNApeSGDLVTPP-LLRILTHIILFLKISGL-AVDEYTSDSIIQAYIELLASAKKVN
  12 -----------..----------------------------------------------------
  13 -----------..----------------------------------------------------
  14 -----------..----------------------------------------------------
  15 -----------..----------------------------------------------------


      430       440       450       460       470       480         490
       |         |         |         |         |         |           |
   1 NIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTTQRVF..DETEQE
   2 NIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTTQRVF..DETEQE
   3 LIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENIC..KKDNGE
   4 LIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENIC..KKDNGE
   5 LIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIR..KKDNGE
   6 LIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIR..KKDNGE
   7 LVPLYIQYLSNQVQYEAYSRFLILVDEESARSEQLQLAKKYSLDINHAALLAVEYVY..DEV---
   8 LVPLYIQYLSNQVQYEAYSRFLILVDEESARSEQLQLAKKYSLDINHAALLAVEYVY..DEV---
   9 MVAFYTAALPPAMQLLLYSQFLQTISDSQQRKQALEQAYNFGLDVPTITVYTVEWYRalEATEDE
  10 LIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRlaHQPLGE
  11 LVPLYIQYLSNQVQYEAYSRFLILVDEESARSEQLQLAKKYSLDINHAALLAVEYVY..DEV---
  12 ---------------------------------------------------------..------
  13 ---------------------------------------------------------..------
  14 ---------------------------------------------------------..------
  15 ---------------------------------------------------------..------


              500            510       520        530       540       5
               |              |         |          |         |        
   1 YSPSN.EISISFDVNNIDM.....HLIYGVEWLIEGKLYV.DAVHSIIALSRRFLLNGRVKALEQ
   2 YSPSN.EISISFDVNNIDM.....HLIYGVEWLIEGKLYV.DAVHSIIALSRRFLLNGRVKALEQ
   3 FSHHDlAPSLDTGTTEEDR.....LKIDVIDWLVFDPAQRaEALRQGNAIMRKFLALKKHEAAKE
   4 FSHHDlAPSLDTGTTEEDR.....LKIDVIDWLVFDPAQRaEALRQGNAIMRKFLALKKHEAAKE
   5 FSHHDlAPSLDTATTEEDR.....LKIDVIDWLVFDPAQRaEALRQGNAIMRKFLALKKHEAAKE
   6 FSHHDlAPALDTGTTEEDR.....LKIDVIDWLVFDPAQRaEALKQGNAIMRKFLASKKHEAAKE
   7 VSVSP.EEVHTVYLKSIEEpv7ykKLICTLEWLLITS-QT.DELLRFANLVYRFFLS--------
   8 VSVSP.EEVHTVYLKSIEEpv7ykKLICTLEWLLITS-QT.DELLRFANLVYRFFLS--------
   9 LTP--.--IASGRLTELDE.....QKISSLEWLTFYPDQRgELLWQSNTLIRYFLARRSIEAARK
  10 FGE--.--PQSGEISAIDQ.....RKISALEWLIHLPEQRgELLWQANAMIRTYLASSKVECMRQ
  11 VSVSP.EEVHTVYLKSIEEpv7ykKLICTLEWLLITS-QT.DELLRFANLVYRFFLS--------
  12 -----.--------NQQPR.....DLPALLQKLHSGPTY-.------------------------
  13 -----.--------NQQPR.....DLPALLQKLHSGEMVH.EAVVRGC-----------------
  14 -----.--------NQQPR.....DLPALLQKLHSGPTY-.------------------------
  15 -----.-------------.....----------------.------------------------


      50          560            570       580         590       600   
      |            |              |         |           |         |   
   1 FMERNN...IGEICKNYELEKIA.....DNISKDENEDQFLE..EITQYEHLIKGIREYEEWQKS
   2 FMERNN...IGEICKNYELEKIA.....DNISKDENEDQFLE..EITQYEHLIKGIREYEEWQKS
   3 VFVKIPqdsIAEIYNQWEEQGME.....SPLPAED--DNAIR..EHLCIRAYLEAHETFNEWFKH
   4 VFVKIPqdsIAEIYNQWEEQGME.....SPLPAED--DNAIR..EHLCIRAYLEAHETFNEWFKH
   5 VFVKIPqdsIAEIYNQWEEQGME.....SPLPAED--DNAIR..EHLCIRAYLEAHETFNERFKH
   6 VFVKIPqdsIAEIYNQCEEQGME.....SPLPAED--DNAIR..EHLCIRAYLEAHETFNEWFKH
   7 ------...IGELNSAYDLYTHIps9lsSSDGEPENDSKFRDayELMNYRALCRALKFYQEWEEL
   8 ------...IGELNSAYDLYTHIps9lsSSDGEPENDSKFRDayELMNYRALCRALKFYQEWEEL
   9 TFAVIP...ADTMELIFTHYGSK.....DDIPCRE--EVSIR..EYLCYQTYLAAIQGYNDWCQL
  10 TFRMVP...ADIVQQLVSLYGSV.....DNIPPRE--ECCLK..EYLCYKAYLSGVDSFVEWNRL
  11 ------...IGELNSAYDLYTHIps9lsSSDGEPENDSKFRDayELMNYRALCRALKFYQEWEEL
  12 ------...----CFIPGVGKWC.....TKLLSEDAKSSTAK..F---------SHPEYFLWQ--
  13 ------...--------------.....--------------..---------------------
  14 ------...----CFIPGVGKWC.....TKLLSEDAKSSTA-..---------------------
  15 ------...--------------.....--------------..---------------------


               610       620              630            640           
                |         |                |              |           
   1 VS.....LLSSESNIPTLIEKLQ..GF.....SKDTFELIKTFLVD.....LTSSN.....FADS
   2 VS.....LLSSESNIPTLIEKLQ..GF.....SKDTFELIKTFLVD.....LTSSN.....FADS
   3 MNs16teKVAYEHREKKYEMDHN..IWk15kmYNVLLFVDGGWMVD.....VREDA.....EDDP
   4 MNs16teKVAYEHREKKYEMDHN..IWk15kmYNVLLFVDGGWMVD.....VREDA.....EDDP
   5 MNs16teKVAHEHKEKKYEMDHN..IWk15kmYNVLLFVDGGWMVD.....VREDA.....EEDP
   6 MNs16teKVAHEHKEKKYEMDFG..IWk15kmYNVLLFVDGGWMVD.....VREDA.....KEDH
   7 SKq23klNFASRKCVKSFTDLLQanWL.....HPSTLEL-------.....---KP.....DDDP
   8 SKq23klNFASRKCVKSFTDLLQanWL.....HPSTLEL-------.....---KP.....DDDP
   9 FYn17teRVTSEHREATYRKELS..NWe15llYNVLLFPEAGWLVDtd6kpPPDDD.....EDWL
  10 QQn27rkEQAHRSEVVRWEHKVK..EQak8llYNVLMFPDKGWLVD.....PFIAKlp7vqLSWD
  11 SKq23klNFASRKCVKSFTDLLQanWL.....HPSTLEL-------.....---KP.....DDDP
  12 --.....----------------..--.....-MNLMLGDISHLLD.....IIWSW.....IAPL
  13 --.....-----------KEQHR..QI.....QMNLMLGDISHLLD.....IIWSW.....IAPL
  14 --.....----------------..--.....--------------.....-----.....----
  15 --.....----------------..--.....--------------.....-----.....----


       650       660        670        680       690       700       71
        |         |          |          |         |         |         
   1 ADYEILYEIRALYTPFLL.MELHKKLV.EAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSG
   2 ADYEILYEIRALYTPFLL.MELHKKLV.EAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSG
   3 ERTHQMVLLRKLCLPMLC.FLLHTILH.STGQYQECLQLADM-------VSSERHKLYLVFSKEE
   4 ERTHQMVLLRKLCLPMLC.FLLHTILH.STGQYQECLQLADM-------VSSERHKLYLVFSKEE
   5 ERAHQMVLLRKLCLPMLC.FLLHTILH.STGQYQECLQLADM-------VSSERHKLYLVFSKEE
   6 ERTHQMVLLRKLCLPMLC.FLLHTILH.STGQYQECLQLADM-------VSSERHKLYLVFSKEE
   7 LLYKTLMTIRNLYVPELI.LGLHNVYF.SLEDYDSCFALANE-------VASEDLKLYHCLIKSG
   8 LLYKTLMTIRNLYVPELI.LGLHNVYF.SLEDYDSCFALANE-------VASEDLKLYHCLIKSG
   9 HRAVQMENLRKLCIPEIV.LLLH----.---QLHTLTERYSENLLLADVLSSETRKLYSVFPKHK
  10 HRLLQMEKLRSICIPEIA.LFLNEVMF.KSGDFAGCVRLADE-------ISSENRQLYKVYTKHK
  11 LLYKTLMTIRNLYVPELI.LGLHNVYF.SLEDYDSCFALANE-------VASEDLKLYHCLIKSG
  12 EDDQS--NFRPHGDPHMIkFGAHMVLVlRLLFTDEINDSFKEKLNNVGDLI---LHMYAMFLFSK
  13 EDDQS--NFRPHGDPHMIkFGAHMVLVlRLLFTDEINDSFKEKLNNVGDLI---LHMYAMFLFSK
  14 -------KFRPHGDPHMIkFGAHMVLVlRLLFTDEINDSFKEKLNNVGDLI---LHMYAMFLFSK
  15 ------------------.--------.-------------------------------------


      0       720      
     |         |      
   1 KLKEYLDLVARTATLSN
   2 KLKEYLDLVARTATLSN
   3 LRKLLQKLRESSLMLLD
   4 LRKLLQKLRESSLMLLD
   5 LRKLLQKLRESSLMLLD
   6 LRKLLQKLRESSLMLLD
   7 RLVEYVSYLGKAGEC--
   8 RLVEYVSYLGKAGEC--
   9 LAETLIKIAESSLTLMN
  10 LAELLAKIADASLELLN
  11 RLVEYVSYLGKAGEC--
  12 QHEELVGIYASQLARHR
  13 QHEELVGIYASQLARHR
  14 QHEELVGIYASQLARHR
  15 -----------------