PFRMAT SS TARGET B AUTHOR SAM-T02 METHOD This file is the result of combining several RDB files, specifically METHOD YCR024C-B.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD YCR024C-B.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD YCR024C-B.t2k.str2.rdb (weight 1.54758) METHOD YCR024C-B.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from YCR024C-B.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET YCR024C-B METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment YCR024C-B.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from YCR024C-B.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET YCR024C-B METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment YCR024C-B.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from YCR024C-B.t2k.str2.rdb METHOD ============================================ METHOD TARGET YCR024C-B METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment YCR024C-B.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ METHOD Comments from YCR024C-B.t2k.alpha.rdb METHOD ============================================ METHOD TARGET YCR024C-B METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment YCR024C-B.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1 METHOD METHOD ============================================ MODEL 1 M C 0.85 C C 0.61 V C 0.50 C C 0.47 A C 0.45 I C 0.53 P C 0.47 F H 0.53 F H 0.63 E H 0.65 F H 0.62 F H 0.54 L H 0.48 P C 0.48 F C 0.50 I C 0.60 P C 0.51 H H 0.49 Y H 0.57 A H 0.52 F E 0.44 L E 0.58 L E 0.63 F E 0.67 V E 0.64 S E 0.52 S E 0.54 V E 0.66 R E 0.73 F E 0.73 T E 0.67 V E 0.50 N C 0.61 E C 0.55 R C 0.45 C E 0.49 Y E 0.60 Y E 0.71 L E 0.77 V E 0.77 C E 0.75 V E 0.68 L E 0.56 K E 0.46 L H 0.44 N H 0.47 C H 0.68 A H 0.80 F H 0.83 F H 0.83 F H 0.79 M H 0.78 V H 0.74 M H 0.71 I H 0.72 F H 0.71 E H 0.65 L H 0.66 K H 0.64 R H 0.59 V H 0.52 C H 0.42 V H 0.42 S H 0.42 Y H 0.40 L C 0.46 D C 0.58 R C 0.56 S C 0.61 R C 0.59 K C 0.49 I E 0.54 Q E 0.65 I E 0.69 V E 0.60 S E 0.52 F E 0.44 F C 0.53 P C 0.49 F E 0.57 I E 0.70 T E 0.73 I E 0.81 I E 0.78 F E 0.71 F E 0.51 H C 0.74 S C 0.92 END