[Genome] genome-mirror at soe.ucsc.edu
Ann Zweig
ann at soe.ucsc.edu
Wed Mar 5 11:28:20 PST 2008
Hello Yongsheng Bai,
The tracks that you are looking at contain genome-wide association
data. Unlike many of our other tracks that annotate specific parts
[start - stop] of the genome, these two tracks simply assign a value to
certain points in the genome. They are meant to be viewed from a more
zoomed-out viewpoint. You can use our Genome Graphs tool to view them
(choose 'Genome Graphs' from the navigation bar on the left side of the
home page). Genome Graphs is a tool for displaying genome-wide data
sets such as the results of genome-wide SNP association studies, linkage
studies and homozygosity mapping.
Specifically, the Case Control Consortium tracks display the trend
p-values (-log10) of the seven diseases reported by The Wellcome Trust
Case Control Consortium. Reported p-values were taken for each of the
Illumina550 probes on the genome. For visualization purposes, these
p-values were logged and negated. For more details see the CCC website:
http://www.wtccc.org.uk/
Likewise for the NIMH tracks: http://nimhgenetics.org/
I hope this information is helpful to you. Please don't hesitate to
contact the mail list again if you require further assistance.
Regards,
----------
Ann Zweig
UCSC Genome Bioinformatics Group
http://genome.ucsc.edu
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Yongsheng Bai wrote:
> Hi,
>
> Could you please tell me how to determine the "ChromEnd" for the following
> tables from your website, since there is only "ChromStart" for them?
>
>> * Bipolar disorder
>> * Coronary artery disease
>> * Crohn's disease
>> * Hypertension
>> * Rheumatoid arthritis
>> * Type 1 diabetes
>> * Type 2 diabetes
>
> Same question for "NIMH Bipolar Disease"?
>> * US (European Descent) — 461 cases in 7 pools, 563 controls in 9
> pools
>> * German — 772 cases in 13 pools, 876 controls in 10 pools
>
> Thanks a lot.
>
> Yongsheng Bai, Ph.D.
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