[Genome] A question on chromsome band

Brooke Rhead rhead at soe.ucsc.edu
Tue Mar 4 20:44:27 PST 2008


Hello Mark,

I also see the ALDOA gene listed at NCBI on 16q22-24.  On OMIM 
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&db=OMIM&term=103850), 
I see a link to "Gene map locus 16q22-q24", in the Entrez record (here: 
http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=34577111), 
I see '/map="16q22-q24"' in the "source" section.

However, I also looked at the gene in NCBI's Map Viewer and Sequence 
Viewer, and they display ALDOA in the exact same position as the Genome 
Browser, on chr16:29,971,973-29,989,236, within 16p11.2:
http://www.ncbi.nlm.nih.gov/projects/sviewer/?id=NC_000016.8&v=29971992-29989236

Ensembl GeneView also shows ALDOA in this region:
http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000149925

I do not know why NCBI has contradictory information on this gene's 
location.  I suggest contacting their helpdesk at info at ncbi.nlm.nih.gov. 
  (And if you find a good explanation, let us know!)

--
Brooke Rhead
UCSC Genome Bioinformatics Group



Mark Tong wrote:
> Hi there, 
> I search gene ALDOA with the following information:
> chr16:29,971,992-29,989,236
> The genome browser tell me this gene is on Chromosome 16 p11.2, and
this is consitenct with the data in table cytoband.
> 
> However, if you check any NCBI web site (entrez, omim, etc, ), it
> will tell you this gene is on chromosome 16 band q22-24.
> I'm not particular about the subband, the p and q make a big
> difference.
> 
> Could any one help me explain this?
> 
> Thanks in advance, 
> 
> 
> Mark Tong, Ph.D. 
> 
> _______________________________________________
> Genome maillist  -  Genome at soe.ucsc.edu
> http://www.soe.ucsc.edu/mailman/listinfo/genome


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