[Genome] A question on chromsome band
Brooke Rhead
rhead at soe.ucsc.edu
Tue Mar 4 20:44:27 PST 2008
Hello Mark,
I also see the ALDOA gene listed at NCBI on 16q22-24. On OMIM
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&db=OMIM&term=103850),
I see a link to "Gene map locus 16q22-q24", in the Entrez record (here:
http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=34577111),
I see '/map="16q22-q24"' in the "source" section.
However, I also looked at the gene in NCBI's Map Viewer and Sequence
Viewer, and they display ALDOA in the exact same position as the Genome
Browser, on chr16:29,971,973-29,989,236, within 16p11.2:
http://www.ncbi.nlm.nih.gov/projects/sviewer/?id=NC_000016.8&v=29971992-29989236
Ensembl GeneView also shows ALDOA in this region:
http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000149925
I do not know why NCBI has contradictory information on this gene's
location. I suggest contacting their helpdesk at info at ncbi.nlm.nih.gov.
(And if you find a good explanation, let us know!)
--
Brooke Rhead
UCSC Genome Bioinformatics Group
Mark Tong wrote:
> Hi there,
> I search gene ALDOA with the following information:
> chr16:29,971,992-29,989,236
> The genome browser tell me this gene is on Chromosome 16 p11.2, and
this is consitenct with the data in table cytoband.
>
> However, if you check any NCBI web site (entrez, omim, etc, ), it
> will tell you this gene is on chromosome 16 band q22-24.
> I'm not particular about the subband, the p and q make a big
> difference.
>
> Could any one help me explain this?
>
> Thanks in advance,
>
>
> Mark Tong, Ph.D.
>
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