[Genome] A question about liftover program

[Shan Yang]

Dear Genome Browser

I am studying a microbial genome that hasn't been fully annotated. It is a substrain of E.Coli K12, which is annotated. Since they are very similar in sequence, I would like to use the K12 annotation for my genome for now. It looks like that liftover program is very suitable for such task. But the problem is that I don't have the chain files between the two strains to run liftover. I am wondering if I can get some idea how to generate such chain files from two fasta files of my microbial genome and K12. I think it is a quite general problem many researchers may run into. So it will be great if you can provide such program on the website.

Thank you very much!

Shan




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