[Genome] Conservation scores

[Brooke Rhead]

Hello Jeffrey,

The hg18 assembly in the Genome Browser has a few tracks that may be 
what you are looking for:

- Conservation
This track shows multiple alignments of 28 vertebrate species and two 
measures of evolutionary conservation -- conservation across all 28 
species and an alternative measurement restricted to the placental 
mammal subset (17 species plus human) of the alignment.

- Most Conserved
This track shows predictions of conserved elements produced by the 
phastCons program based on a whole-genome alignment of vertebrates, and 
for the placental mammal subset of species in the alignment.

- TFBS Conserved
This track contains the location and score of transcription factor 
binding sites conserved in the human/mouse/rat alignment.

You can read more details about each track by clicking on its name in 
the Genome Browser, or by clicking the "mini-button" for the track -- 
the thin blue or gray bar to the far left of the track in the main 
Genome Browser display.

I hope one of these tracks is helpful.  Please feel free to contact us 
again at this mailing list address if we can be of further assistance.

--
Brooke Rhead
UCSC Genome Bioinformatics Group


Jeffrey Rosenfeld wrote:
> Hi,
> 
> 	I am trying to find conservation scores for a human/rat/mouse  
> alignment from hg18.  I looked around your site, but I couldn't find  
> it.  Do you have such a file, or would it be easy to make one?
> 
> Thank You,
> Jeffrey Rosenfeld
> Cold Spring Harbor Laboratory
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