[Genome] track for duplication loci
Robert Kuhn
kuhn at soe.ucsc.edu
Thu Nov 8 16:16:42 PST 2007
Dr. Wistow,
We do have a track of data from Eichler's lab, Segmental Dups,
last updated 2006-07-14. We will look into whether the data
in the papers you cite are available for inclusion in the
Browser.
Thank you for bringing these data to our attention.
best wishes,
--b0b kuhn
ucsc genome bioinformatics group
> From genome at soe.ucsc.edu Thu Nov 8 09:32:57 2007
> To: <genome at soe.ucsc.edu>
> Subject: [Genome] track for duplication loci
>
> Evan Eichler and others have identified regions of the human genome that
> are subject to duplication/deletion and can act as hot spots for
> recombination:
>
> For example:
>
> Jiang Z, Tang H, Ventura M, Cardone MF, Marques-Bonet T, She X, Pevzner
> PA, Eichler EE.
>
> Ancestral reconstruction of segmental duplications reveals punctuated
> cores of human genome evolution.
>
> Nat Genet. 2007 Nov;39(11):1361-8.
>
>
>
> Cooper GM, Nickerson DA, Eichler EE.
>
> Mutational and selective effects on copy-number variants in the human
> genome.
>
> Nat Genet. 2007 Jul;39(7 Suppl):S22-9.
>
>
>
> Is there a browser track that indicates the relative positions of these
> regions on the current build or is one on the way?
>
> Graeme Wistow Ph.D.
> Chief, Section on Molecular Structure and Functional Genomics,
> National Eye Institute,
> 7/201, NIH,
> Bethesda, MD 20892-0703 USA
> Tel: 301-402-3452
> Fax: 301-496-0078
> Email: graeme at helix.nih.gov
>
>
>
> _______________________________________________
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