[Genome] track for duplication loci

Robert Kuhn kuhn at soe.ucsc.edu
Thu Nov 8 16:16:42 PST 2007


Dr. Wistow,

We do have a track of data from Eichler's lab, Segmental Dups,
last updated 2006-07-14.  We will look into whether the data
in the papers you cite are available for inclusion in the
Browser.  

Thank you for bringing these data to our attention.

best wishes,

			--b0b kuhn
			ucsc genome bioinformatics group


> From genome at soe.ucsc.edu  Thu Nov  8 09:32:57 2007
> To: <genome at soe.ucsc.edu>
> Subject: [Genome] track for duplication loci
> 
> Evan Eichler and others have identified regions of the human genome that
> are subject to duplication/deletion and can act as hot spots for
> recombination:
> 
> For example:     
> 
> Jiang Z, Tang H, Ventura M, Cardone MF, Marques-Bonet T, She X, Pevzner
> PA, Eichler EE.          
> 
> Ancestral reconstruction of segmental duplications reveals punctuated
> cores of human genome evolution.
> 
> Nat Genet. 2007 Nov;39(11):1361-8. 
> 
>  
> 
> Cooper GM, Nickerson DA, Eichler EE.   
> 
> Mutational and selective effects on copy-number variants in the human
> genome.
> 
> Nat Genet. 2007 Jul;39(7 Suppl):S22-9. 
> 
>  
> 
> Is there a browser track that indicates the relative positions of these
> regions on the current build or is one on the way?
> 
> Graeme Wistow Ph.D. 
> Chief, Section on Molecular Structure and Functional Genomics, 
> National Eye Institute, 
> 7/201, NIH, 
> Bethesda, MD 20892-0703 USA 
> Tel: 301-402-3452 
> Fax: 301-496-0078 
> Email: graeme at helix.nih.gov 
> 
>  
> 
> _______________________________________________
> Genome maillist  -  Genome at soe.ucsc.edu
> http://www.soe.ucsc.edu/mailman/listinfo/genome
> 


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