[Genome] UCSC Genome Browser can't locate certain accession numbers present in GenBank

[Rachel Harte]

Dear Lee Tuan Meng,

The reason for this is that these accession numbers beginning with "CR"
are for sequences from Invitrogen. We heard that some of these Invitrogen
cDNA sequences had been altered to make them identical to the NCBI human
genome assembly sequence. Therefore they can not be trusted as
representing mRNA transcripts. So we decided to exclude all of these
accessions from our Genbank sequence alignments.

I hope that this helps you. Please let us know if you have further
questions.

Rachel

Rachel Harte
UCSC Genome Bioinformatics Group
http://genome.ucsc.edu


On Thu, 21 Jun 2007, #LEE TUAN MENG# wrote:

> I have some accession numbers which UCSC Genome Browser cannot locate, but is present in GenBank.
>
> 1 of them is CR593711. In UCSC Genome Browser, it gives me the following:
>
> "Sorry, couldn't locate CR593711 in genome database."
>
> But in GenBank, it is there @  http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=50474518
>
> Concidentally, the accession numbers that are giving me problems all seem to start with "CR", while I have no problems with the other accession numbers.
>
> Is there any explanation for?
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