[Genome] Fwd: cool
Tim Hefferon
thefferon at mail.nih.gov
Thu Jun 7 14:00:52 PDT 2007
Kate,
I sent these to the general help address earlier, but didn't get a
response. (Same with the next e-mail.)
Can you please help answer the question? I find myself in need of
this tool again.
Thanks,
Tim
Begin forwarded message:
> From: Tim Hefferon <timhefferon at gmail.com>
> Date: April 22, 2007 7:23:11 AM GMT-06:00
> To: genome at soe.ucsc.edu
> Subject: cool
>
> Hi,
>
> Jim Kent's Perfect Match to Short Sequence feature is useful.
>
> What would make it extremely useful is if it could search for
> degenerate matches, using the IUPAC code.
>
> Let's say, for example, that I am interested in finding binding
> sites for a transcription factor or a splicing factor, whose
> binding site is AG(Py)TG(Pu). If the feature I request were
> available, I could simply enter 'AGYTGR' and BANG - there are all
> the potential binding sites for that protein.
>
> Please ask Jim whether it would be a simple matter to include this
> feature. As an aside, it would be helpful if, on the page where one
> enters the sequence to be searched, there were a summary of the
> IUPAC code for reference.
>
> Thank you!
>
> Tim Hefferon
>
>
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