[Genome] Help!

[Kayla Smith]

Wen-Xin,


Yes, you are correct.  The region you mention,
chr15:38,117,768-38,117,890 is within an exon of the SRP14 gene.  The
large peak in the Conservation track at chr15: 38,117,568-38,117,968
implies that the sequence there is conserved.

You can click into the details page for the conservation track and check
the boxes to turn on information for any/all of the aligning species in
order to determine more specifically which species have sequence in
common.  Good luck with your research.

I hope this is helpful to you.  Please don't hesitate to contact us
again if you require further assistance.

Kayla Smith
UCSC Genome Bioinformatics Group


ZhengWenXin wrote:
> Dear Prof.
>       I query the sub-sequence from 38,117,568-38,117,968 on the chromosome 15 of the human genome (hg18, Mar 2006) through the Genome Browser. It can be seen that there’s a gene named SRP14 aligning there in the RefSeq Genes track. I want to make it sure that if the region from about 38,117,768-38,117,890 bp, represented by a piece of thick line, is an exon of the gene named SRP14. If it is an exon of the gene SRP14, please see the conservation track of the region chr15: 38,117,568-38,117,968. There’s a large peak in the region of this exon in the conservation track. Does it mean that this exon is more conserved than the introns beside it throughout evolution? 
> Thanks a lot for your patience. I am looking forward to hearing from you. Your help to my study would be greatly appreciated.
>  
> Best wishes,
> Wen-Xin
>  
> Wen-Xin Zheng, PhD candidate
> Bioinformatics Center
> Tianjin University
> Tianjin 300072
> China
> Fax: +86-22-27402697
> Website: http://tubic.tju.edu.cn
>  
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