[Genome] A question about regulatory potential scores (regPotential7X.txt for mouse)

[Shan Yang]

Hi,

I just downloaded the "regPotential7X.txt" file for mm8. Here is a 
question I have about the data.
For example, the 1st line in the file says:

608     chr1    3050242 3050650 
chr1.0  1       408     0       /gbdb/mm8/wib/regPotential7X.wib 
   0       0.144514        408     1.67677 0.187318

To my understanding, this basically means that the 408 bp long region 
has a min score of 0 and max score of 0.144514 and the sum of score 
in this region is 1.67677, which makes the average to be 0.00408028. 
According to the description of this score, anything over 0.001 may 
have a big potential to be a regulatory element, which means this 
regions is highly possible to be a regulatory element. But if I look 
at the browser, I can see that the main contributor of this average 
score in this 408bp region is a subregion of chr1:3050626-3050650 
(25bp). So does this mean that this subregion has more potential than 
any other nt in this region or every nt in this entire 408 bp region 
has the same potential? I think the first should be right. If this is 
true, then why does the file record the whole 408 region rather than 
just the subregion?

Thanks a lot!

Shan


Shan Yang, PhD
Genome Biology Division, L-452
Chemistry,  Materials & Life Sciences Directorate (CMLS)
Lawrence Livermore National Laboratory
7000 East Ave, Livermore, CA, 94550

Ph:  925-422-7389
Fax: 925-422-2099