[Genome] about hg18_Build36

[Daryl Thomas]

Jun,

I'd like to elaborate on Fan's answer to put the differences in context.

Each of NCBI's new genome assemblies is given a build identifier.  NCBI's build 36 is the same as our hg18.

NCBI then updates the annotation for this assembly periodically.  The annotations are described by their suffix, so the first
annotation for this assembly is 36.1.  The next annotation release would be 36.2, but the underlying sequence remains the same.  

When discussing the sequence assembly alone, then Build 36 is the same as Build 36.1 (and Build 36.2 ...).

Daryl

> -----Original Message-----
> From: genome-bounces at soe.ucsc.edu 
> [mailto:genome-bounces at soe.ucsc.edu] On Behalf Of Fan Hsu
> Sent: Wednesday, January 31, 2007 9:20 PM
> To: Jun Wang; genome at soe.ucsc.edu
> Subject: Re: [Genome] about hg18_Build36
> 
> 
> Hi Jun,
> 
> Build 36 is Build 36.1.
> 
> Fan.
> -----Original Message-----
> From: genome-bounces at soe.ucsc.edu 
> [mailto:genome-bounces at soe.ucsc.edu]On
> Behalf Of Jun Wang
> Sent: Wednesday, January 31, 2007 6:17 PM
> To: genome at soe.ucsc.edu
> Subject: [Genome] about hg18_Build36
> 
> 
> Hello,
> 
>       I tried to download the human chromosome sequences from
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/chromosomes/
> whose last modified date is 09-Dec-2005,
> are those sequences from Build 36 rather than Build 36.1?
> What could be the differences between Build36 and Build 36.1 for  
> these sequences?
> 
>     Previously, I also downloaded the best reciprocal chain file  
> between hg18 and panTro2 from
> http://hgwdev.cse.ucsc.edu/goldenPath/hg18/vsPanTro2/ 
> hg18.panTro2.rbest.chain.gz
>   if I wanna extract the corresponding human sequences, which 
> version  
> I should use, Build 36 or Build 36.1 ?
> 
> Thanks a lot
> 
> Jun Wang
> PhD candidate
> University of Chicago
> 1101 E 57th ST.
> Chicago, IL, 60637
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