[Genome] [Fwd: GoldenPath]

Rachel Harte hartera at soe.ucsc.edu
Tue Jan 2 10:22:25 PST 2007


Loren,

The "Golden Path" is the assembled genome sequence. This term was
originally applied to the human genome assemblies at UCSC but it is also
now used for other genome assemblies. If you go to the human Genome
Browser and click on the "Assembly" link above the Assembly track control
in the "Mapping and Sequencing Tracks" group then you will see the
description for this track. Here it is:

"This track shows the draft assembly of the human genome. This assembly
merges contigs from overlapping drafts and finished clones into longer
sequence contigs. The sequence contigs are ordered and oriented when
possible by mRNA, EST, paired plasmid reads (from the SNP Consortium) and
BAC end sequence pairs.

In dense mode, this track depicts the path through the draft and finished
clones (aka the golden path) used to create the assembled sequence. Clone
boundaries are distinguished by the use of alternating gold and brown
coloration. Where gaps exist in the path, spaces are shown between the
gold and brown blocks. If the relative order and orientation of the
contigs between the two blocks is known, a line is drawn to bridge the
blocks."

I hope that this answers your question. In the future, please direct your
questions to the genome mailing list at genome at soe.ucsc.edu - our
moderated forum for user questions and discussion. You should then get a
faster response to your question. Thanks.

Rachel

 > -------- Original Message --------
> Subject: 	GoldenPath
> Date: 	Mon, 01 Jan 2007 20:27:13 -0800
> From: 	Loren Engrav <engrav at u.washington.edu>
> To: 	<cbseweb at cbse.ucsc.edu>
>
>
>
> What does goldenPath mean? What does it refer to?
>
> Thanks
>
>
> ---from
>
> ...all creatures great and small...
>
> Loren H. Engrav, MD
> Professor, Division of Plastic Surgery
> Harborview Med Ctr, 359796
> 325 Ninth Avenue
> Seattle, WA 98104
> office 206 731 3209
> fax 206 731 3656
> email engrav at u.washington.edu
>
>
>
>
>
> --
> Branwyn Stewart Wagman
> Communications & Human Resources
> Center for Biomolecular Science and Engineering (CBSE)
> Institute for Quantitative Biomedical Research (QB3)
> 501C Engineering 2 Building
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>


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