[Genome] mutually exclusive exons
Ann Zweig
ann at soe.ucsc.edu
Fri Dec 7 13:32:54 PST 2007
Hello Pete,
We have only enumerated the following alternative splicing and other
events in the knownAlt table:
* Alternate Promoter (altPromoter) - Transcription starts at
multiple places.
* Alternate Finish Site (altFinish) - Transcription ends at
multiple places.
* Cassette Exon (cassetteExon) - Exon is present in some
transcripts but not others. These are found by looking for exons that
overlap an intron in the same transcript.
* Retained Intron (retainedIntron) - Introns are spliced out in
some transcripts but not others. In some cases, particularly when the
intron is near the 3' end, this can reflect an incompletely processed
transcript rather than a true alt-splicing event.
* Overlapping Exon (bleedingExon) - Initial or terminal exons
overlap in an intron in another transcript. These often are associated
with incompletely processed transcripts.
* Alternate 3' End (altThreePrime) - Variations on the 3' end of an
intron.
* Alternate 5' End (altFivePrime) - Variations on the 5' end of an
intron.
* Intron Ends have AT/AC (atacIntron) - An intron with AT/AC ends
rather than the usual GT/AG. These are associated with the minor
spliceosome.
* Strange Intron Ends (strangeSplice) - An intron with ends that
are not GT/AG, GC/AG, or AT/AC. These are usually artifacts of some sort
due to sequencing error or polymorphism.
Depending on exactly what output you are trying to get, you might be
able to create this on your own using the Custom Track tool. You can
read about it here:
http://genome.cse.ucsc.edu/goldenPath/help/customTrack.html
Regards,
----------
Ann Zweig
UCSC Genome Bioinformatics Group
http://genome.ucsc.edu
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Pete Shepard wrote:
> Dear Genome Browser Folks,
>
> I am wondering if you have a field for mutually exclusive exons in your
> knownAlt table.
>
> Thanks
> _______________________________________________
> Genome maillist - Genome at soe.ucsc.edu
> http://www.soe.ucsc.edu/mailman/listinfo/genome
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