[Genome] Finding orthologous genes

[Kayla Smith]

Hello Keren,

Within many species (human, mouse, rat...) we have xxBlastTab tables 
which try to combine chains with BLAT homology searching to arrive at a 
set of true orthologs across-species.

To find orthologs, first you would have to get a mapping from your 
pseudogene to a human knownGene.  Then you could go from that to another 
species via one of the xxBlastTab tables.

I hope this information is helpful to you.  Please don't hesitate to 
contact us again if you require further assistance.

Kayla Smith
UCSC Genome Bioinformatics Group





Keren Avital wrote:
> Hello, 
> 
> I have several hundreds of  human pseudogenes, and I like to find known functonal orthologous genes in other species.
> What is the best way to find functonal orthologous gene?
> 
> Thanks, 
> Keren
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