[Genome] 500 kb BACs?

[Katie Rudd]

In the March 2006 assembly, there are some BACs that appear to be  
much larger than expected.  For example, AC025983.3 (RP11-687M15)  
spans greater than 500 kb on the chromosome 19 browser view, but  
according to NCBI it is 173 kb in 35 unordered pieces.  Several other  
BACs in the same region also span regions much larger than the  
average BAC insert size.  There are no annotated segmental  
duplications in this region, so I can't imagine why these BACs would  
be assembled to cover such a large space.  Any reason for this?

Katie Rudd, Ph.D.
postdoc, Trask Lab
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. North
C3-111
Seattle, WA 98109

206-667-1471

mrudd at fhcrc.org