[Genome] Human Promoters

[Liron Levkovitz]

Hello Mike,

Thanks for your answer. I just want to make sure I understand: In case the
promoters have different RefSeq IDs but the same locations-  they are
promoters of splice variants (as a results from alternative splicing), and
in the case they have the same RefSeq IDs but different locations- they are
alternative promoters of the same gene (see example below).

>NM_000039_up_1000_chr11_116213549_r
>NM_000039_up_1000_chr22_random_12498_f  

Is this correct?

Thanks
Liron Levkovitz
M.Sc student
Tel Aviv University

-----Original Message-----
From: Mike Mitchell [mailto:Mike.Mitchell at cancer.org.uk] 
Sent: Thursday, November 02, 2006 6:17 PM
To: Liron Levkovitz; 	
Subject: Re: [Genome] Human Promoters

This is an example of known gene isoforms (splice variants).

The gene UBE2J2 has 4 known isoform, each one of these has it's own RefSeq
identifier and in this case they all share the same first exon. If you have
a look at hg18 at chr1:1,179,157-1,199,097 you will see the case that you
highlighted.

--
Mike Mitchell
Bioinformatics & Biostatistics Service
Cancer Research UK +44 (0) 207 269 3115


 
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