[Genome] Data is incorrect
inouetds@chugai-pharm.co.jp
inouetds at chugai-pharm.co.jp
Thu Dec 14 03:16:58 PST 2006
Hellow support team
I found an incorrect data on your homepage, as below.
Please check the reference and correct it?
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Description: erythropoietin precursor
Alternate Gene Symbols: BC093628, BC111937, X02157
Representative Refseq: NM_000799 Protein: P01588 <http://www.expasy.org/cgi-bin/niceprot.pl?P01588> (aka EPO_HUMAN)
RefSeq Summary: This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
PHARMACEUTICAL: Used for the treatment of anemia. Available under the names Epogen (Amgen), Epogin (Chugai), Epomax (Elanex), Eprex (Janssen-Cilag), NeoRecormon or Recormon (Roche), and Procrit (Ortho Biotech). Variations in the glycosylation pattern of EPO distinguishes these products. Epogen, Epogin, Eprex and Procrit are generically known as epoetin alfa, Epogin (/Marogen), NeoRecormon and Recormon as epoetin beta and Epomax as epoetin omega.
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Reference
USPDI
Epoetin Beta PrintClose
Date [1990].
Molecular Info C809H1301N229O240S5 (amino acid sequence). 18,236.06.
Nonproprietary Name INN; BAN; JAN.
Chemical Name A 165 amino acid glycoprotein (approximately 62% protein and 38% carbohydrate by weight; total molecular weight of about 30,000 daltons) that regulates red blood cell production. Epoetin Beta is produced by the Chinese hamster ovary DN2-323 recombinant cell line. (1) 1-165-Erythropoietin (human clone lHEPOFL13 protein moiety) glycoform b; (2) 1-165-Erythropoietin (human clone lHEPOFL13 protein moiety), glycoform b.
CAS Numbers CAS-122312-54-3.
Category Anti-anemic; hematinic.
Manufacturer Info Marogen (Chugai Pharmaceutical Co., Ltd., Japan)
Code Designations EPOCH; BM 06.019
More information about the Genome
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