BME/BIO 210: Application and Analysis of (Biological) Microarrays
Spring Quarter, 2007
Class Presentations
Class presentations will be one full class session, with ~25-30
minutes oral presentations giving background
on the technique, applications, and types of data produced. The
remainder of the session the group will review
one paper representative of the methodology and the problems it
addresses. Groups will be 2-3 people per group,
with 6 groups total.
Suggested Topics
- Clinical typing of cancer cells
by microarray analysis
- Host-pathogen interactions with
microarrays
- ChIP Chip screen for
transcription factor binding sites
- "Next generation" high
throughput sequencing
- ABI SOLiD Sequencing
- Illumina / Solexa Genetic
Analyzer
- 454 / Roche sequencers
- SNP discovery with high density
arrays
- Protein or antibody arrays
- Synthetic lethal screens
- Microbial strain bar-coding
- Small molecule screens for
- 2D-protein gels and tandem mass
spectrometry
- Yeast two-hybrid and
three-hybrid screens to detect protein or RNA mediated interactions
- Tissue arrays
- Methods for establishing gene
regulatory networks
- (propose your own)
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