BME 088a: Surfing Your Genome

Winter Quarter, 2003

Time: Th 10-11:45am

Location: Lectures: Baskin 156

Course Info Link: www.soe.ucsc.edu/classes/bme088a/Winter03/

Instructor	Todd Lowe
Email	lowe@soe
Phone	459-1511
Office	227 Sinsheimer
Office Hours	Wed 3:30-4:30, Thur 2-3pm & by appt.

Announcements / Updates

Feb 6: Change in schedule -- David Haussler speaking next week (2/13), and student presentations will follow next week (2/20) (see below)
Feb 6: Class links added / list of topics to be covered in your genome assignment
Jan 30: Class Topics Schedule updated
Jan 22: Readings & assignments page posted (see link below)
Jan 17: Class website posted!

Readings, Class Web Links & Assignments

Student Genome Presentations

Grading

50%	Participation
35%	"Your Gene" 10 min class talk
15%	Final Quiz (last day of class)

Lecture & Discussion Topics

Date	Topic
January 9	Overview of Course	NOVA Special: Cracking the Code of Life, Part I
January 16	Some Genome Terms	NOVA Special: Cracking the Code of Life, Part II
January 23	A Guided Tour of the UCSC Human Genome Browser	Guest speaker: Jim Kent
January 30	Discussion, Genome Chapters 1-3	LUCA, The RNA World Hypothesis Speciation, subtle genetic differences between us & other primates Link between genetic mutation & phenotype (Alkaptonuria) Practice with the Genome Browser
February 6	Resequencing Genomes -- Today! Genetic Determinism (Discussion, Genome, Chapters 4 & 5)	Guest Speaker: Renee Stokowski, Perlegen Sciences
February 13	Bioinformatics Research at Santa Cruz	Guest Speaker: David Haussler
February 20	Short Student Genome Presentations
February 27	Student Presentations
March 6	Cancelled, rescheduled for March 11
March 11	Last of Student Presentations Functional Genomics: Using DNA Microarrays
March 13	Discussion of topics from "Genome" book reading Final Quiz / Wrap-up